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venerdì 20 gennaio 2017

# s-ageing: epigenetic regulation of ageing

<< In  vitro  cellular reprogramming through the expression of the four transcription factors OCT4, SOX2, KLF4 and MYC (OSKM) has been shown to ameliorate age-associated cellular phenotypes, including gene  expression  profiles,  telomere length and oxidative stress >>

Kim Baumann. Forever young. Nature Reviews Molecular Cell Biology. Publ online 5 Jan 2017; doi:10.1038/nrm.2016.176

http://www.nature.com/nrm/journal/vaop/ncurrent/full/nrm.2016.176.html

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