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lunedì 23 gennaio 2017

# s-cells: disassembling to create undifferentiated (stem) entities

AA << have  published a study demonstrating how specialized proteins are  able to  change  the identity, or cellular  characteristics,  of skin cells and  create induced  pluripotent  stem cells, which have  the ability to turn into  any cell type  in  the  body. >>

Mirabai Vogt-James. Study pinpoints how skin cells' identity can be disassembled to create stem cells. Jan 20, 2017.

https://m.phys.org/news/2017-01-skin-cells-identity-disassembled-stem.html

<< Oct4, Sox2, Klf4, and cMyc (OSKM) reprogram somatic cells to pluripotency. >>

Constantinos Chronis, Petko Fiziev, Bernadett Papp et al. Cooperative Binding of Transcription Factors Orchestrates Reprogramming. Cell (2017). DOI: 10.1016/j.cell.2016.12.016 Publ. Jan.19, 2017

http://www.cell.com/cell/abstract/S0092-8674(16)31730-5

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