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mercoledì 1 marzo 2017

# s-gene: epigenetic 'cis' and 'trans' memories

<< How epigenetic memory is stored and inherited is an on-going debate (..). In so-called  ‘cis  memory’, epigenetic information is proposed to be physically stored in local chromatin states that are associated, for example, with DNA methylation or histone modifications. By contrast, in  ‘trans  memory’, epigenetic information is stored in the concentration of a diffusible factor such as a transcriptional repressor. >>

Caroline Dean. What holds epigenetic memory? Nature Reviews Molecular Cell Biology Volume: 18, Page: 140 Year published: (2017) DOI: doi:10.1038/nrm.2017.15 Published online 21 February 2017

http://www.nature.com/nrm/journal/v18/n3/full/nrm.2017.15.html

more:

https://www.ncbi.nlm.nih.gov/m/pubmed/?term=epigenetic+memory

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