venerdì 11 dicembre 2015

# rmx-s-behav: to sense environment, then dipping

<< On its surface, a bacterium has thousands of receptors that scan the environment and then tell it what to do >>

<< The receptors on the surface of a bacterial cell detect light, chemicals, edible things and poisonous things, and transmit that information to a deeper layer of proteins, called kinases, which interpret this data and translate it into a simple choice: “Keep going” or “Change direction!” >>

<< (..) one region of a kinase called CheA, changes its orientation in relation to the other proteins, in a motion called “dipping.” >>

C Keith Cassidy, Benjamin A Himes,  et al. CryoEM and computer simulations reveal a novel kinase conformational switch in bacterial chemotaxis signaling. eLife, 2015; 4 DOI: 10.7554/eLife.08419

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