# gene: knockdown of a single gene, the generation of a third eye (in scarabaeid beetles)

<< The creation of three-eyed beetles through a new technique (..) provides scientists a new way to investigate the genetic mechanisms responsible for the evolutionary emergence of new physical traits >>

Kevin Fryling. Biologists create beetle with functional extra eye. Nov 13, 2017

https://m.phys.org/news/2017-11-biologists-beetle-functional-extra-eye.html

AA << report the ectopic induction of complex and functional organs, compound eyes, by down-regulation of a single transcription factor through RNAi, a technique known to work well across a broad taxonomic range >>

AA << results show that knockdown of a single gene is sufficient for the middorsal head to acquire the competence to ectopically generate a functional compound eye-like structure >>

Eduardo E. Zattara, Anna L. M. Macagno, et al. Development of functional ectopic compound eyes in scarabaeid beetles by knockdown of orthodenticle. PNAS. 2017; 114 (45): 12021–6

http://m.pnas.org/content/114/45/12021