# gene: newtic1 to regenerate limbs

<< The newt, a group of urodele amphibians, has outstanding ability to repeatedly regenerate various body parts >>

<< In this animal, when the limb is amputated, a cell mass named the blastema appears on the stump and eventually gives rise to a new functional limb >>

AA << identified an orphan gene Newtic1, whose transcripts significantly increased in the blastema. Newtic1 was expressed in a subset of erythrocytes that formed a novel clump (EryC) >>

<< When the limb was amputated, EryCs were newly generated in the stump and accumulated into a distal portion of the growing blastema. >>

Roman M. Casco-Robles, Akihiko Watanabe, et al. Novel erythrocyte clumps revealed by an orphan gene Newtic1 in circulating blood and regenerating limbs of the adult newt. Scientific Reports. 8 (7455). May 10, 2018.

https://www.nature.com/articles/s41598-018-25867-x

Novel gene in red blood cells may help adult newts regenerate limbs. University of Tsukuba. Jun 5, 2018.

https://m.phys.org/news/2018-06-gene-red-blood-cells-adult.html

Also

# gene: the ability of the newt to safely regenerate parts of itself. Dic 30, 2017

https://flashontrack.blogspot.com/2017/12/gene-ability-of-newt-to-safely.html