sabato 6 luglio 2019

# brain: short-term exercise enhances brain function

<< Exercise is cheap, and you don't necessarily need a fancy gym membership or have to run 10 miles a day, >> Gary Westbrook

AA << designed a study in mice that specifically measured the brain's response to single bouts of exercise in otherwise sedentary mice that were placed for short periods on running wheels. The mice ran a few kilometers in two hours. >>

<< short-term bursts of exercise- the human equivalent of a weekly game of pickup basketball, or 4,000 steps- promoted an increase in synapses in the hippocampus. Scientists made the key discovery by analyzing genes that were increased in single neurons activated during exercise. >>

<< One particular gene stood out: Mtss1L. This gene had been largely ignored in prior studies in the brain. >>

Study reveals a short bout of exercise enhances brain function. Oregon Health & Science University.  Jul 3, 2019.

https://m.medicalxpress.com/news/2019-07-reveals-short-bout-brain-function.html   

AA << results link short-term effects of exercise to activity-dependent expression of Mtss1L, which propose as a novel effector of activity- dependent rearrangement of synapses. >>

Christina Chatzi, Yingyu Zhang, et al.  Exercise-induced enhancement of synaptic function triggered by the inverse BAR protein, Mtss1L.  eLife 2019; 8: e45920. doi: 10.7554/eLife.45920. Jun 24, 2019

https://elifesciences.org/articles/45920 

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