# gene: parental 'memory' could be inherited across generations

AA << tested the possibility that environmentally triggered modifications could allow 'memory' of parental experiences to be inherited. In Drosophila melanogaster, exposure to predatory wasps leads to inheritance of a predisposition for ethanol-rich food for five generations.  Inhibition of Neuropeptide-F (NPF) activates germline caspases required for transgenerational ethanol preference. Further, inheritance of low NPF expression in specific regions of F1 brains is required for the transmission of this food preference >>

<< Given the conserved signaling functions of NPF and its mammalian NPY homolog in drug and alcohol disorders, these observations raise the intriguing possibility of NPY-related transgenerational effects in humans. >>

Julianna Bozler, Balint Z Kacsoh, Giovanni Bosco. Transgenerational inheritance of ethanol preference is caused by maternal NPF repression.
eLife doi: 10.7554/eLife.45391.001. Jul 9, 2019.

https://elifesciences.org/articles/45391

Study finds that parental 'memory' is inherited across generations. The Geisel School of Medicine at Dartmouth. Jul 9, 2019.

https://m.phys.org/news/2019-07-parental-memory-inherited.html   

Also

"Neuropeptide-F"

https://www.ncbi.nlm.nih.gov/mesh/?term=Neuropeptide-F

http://flybase.org/reports/FBgn0027109.html 

https://www.wikigenes.org/e/gene/e/42018.html