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domenica 13 dicembre 2015

# rmx-p-it: ovvia, idonea risposta a cluster comportamentali noti, reiterati, arcaici perfino ...

<< Banca Etruria (..) la procura di Civitavecchia ha aperto un’indagine per istigazione al suicidio >>

Alessandro De Angelis, L'Huffington Post, 12/12/2015

http://m.huffpost.com/it/entry/8794278

<< divagando, accennai in tempi non sospetti (6,7 anni fa):  "dipende ..., ditino- telefonino potrebbe  non aiutare, anzi ..." >> Anonymous, 13/12/2015

# rmx-s-gene: focusing on clusters of biochem tweets: untranslated UTR elements to silencing

<< (..) the first library built for researchers to explore genes’ deep and hidden messages >>

<< Small RNAs (miRNAs) work to pair with a UTR to block translation, killing the message, and thus, silencing a gene. Uncovering the interplay between miRNA and their specific UTRs have become a hot area in biology, and big business >>

https://biodesign.asu.edu/news/new-asu-worldwide-resource-exploring-genes%e2%80%99-hidden-messages

Kasuen Kotagama, Cody S. Babb, et al. A human 3′UTR clone collection to study post-transcriptional gene regulation. BMC Genomics. DOI 10.1186/s12864-015-2238-1

http://www.biomedcentral.com/1471-2164/16/1036

The library

http://dnasu.asu.edu

# s-lab: rapid detection of biomarkers: birefringence

<< (..) a new diagnostic method. It is based on Birefringence, the ability of substances to change the polarisation state of light. With this method, doctors around the world can easily, rapidly and reliably detect malaria, Ebola or HIV to name only a few >>

https://www.ethz.ch/en/news-and-events/eth-news/news/2015/12/diagnostics-with-birefringence.html

Jijo J. Vallooran, Stephan Handschin, et al. Lipidic Cubic Phases as a Versatile Platform for the Rapid Detection of Biomarkers, Viruses, Bacteria, and Parasites. Advanced Functional Materials, 2015, December 4; DOI: 10.1002/adfm.201503428

http://onlinelibrary.wiley.com/doi/10.1002/adfm.201503428/abstract

# rmx-s-gst-ecol: about biodiversity studies

<< Many of the previous studies on global species diversity are inaccurate >>

<< (..) there might be an under- or overestimation of global biodiversity by up to 50 per cent when the survey is based on only a few taxa >>

https://www.idiv.de/en/press/press-releases/press_release_single_view/article//study-finds.html

Schuldt, A., Wubet, T., et al. Multitrophic diversity in a biodiverse forest is highly nonlinear across spatial scales. Nature Communications 6: 10169. DOI: 10.1038/ncomms10169.

http://dx.doi.org/10.1038/ncomms10169 

# rmx-s-behav: delay discounting

<< 'Delay discounting' is the tendency, given the choice, to take a smaller reward that is available immediately, instead of a larger reward that will be delivered in the future >>

<< delay discounting is strongly influenced by our genetic makeup. That is, it is a trait that can be inherited >>

<< preliminary data suggest that these 'impulsivity genes' may include genes coding for enzymes that synthesize the neurotransmitter serotonin and receptors where serotonin binds in the brain >>

http://www.eurekalert.org/pub_releases/2015-12/acon-iym120615.php

Andrey Anokhin et al. American College of Neuropsychopharmacology annual meeting in Hollywood, Florida,  december 6-10, 2015

http://www.acnp.org/annualmeeting/default.aspx

# rmx-s-tech: a wearable generator

<< the first self-sufficient system powered by a wearable energy generator based on microbial fuel cell technology >>

http://www.alphagalileo.org/ViewItem.aspx?ItemId=159287&CultureCode=en

M Taghavi, A Stinchcombe,  et al. Self sufficient wireless transmitter powered by foot-pumped urine operating wearable MFC. Bioinspiration & Biomimetics, 2015; 11 (1): 016001 DOI: 10.1088/1748-3190/11/1/016001

http://m.iopscience.iop.org/article/10.1088/1748-3190/11/1/016001/

venerdì 11 dicembre 2015

# rmx-s-behav: to sense environment, then dipping

<< On its surface, a bacterium has thousands of receptors that scan the environment and then tell it what to do >>

<< The receptors on the surface of a bacterial cell detect light, chemicals, edible things and poisonous things, and transmit that information to a deeper layer of proteins, called kinases, which interpret this data and translate it into a simple choice: “Keep going” or “Change direction!” >>

<< (..) one region of a kinase called CheA, changes its orientation in relation to the other proteins, in a motion called “dipping.” >>

https://news.illinois.edu/blog/view/6367/290048

C Keith Cassidy, Benjamin A Himes,  et al. CryoEM and computer simulations reveal a novel kinase conformational switch in bacterial chemotaxis signaling. eLife, 2015; 4 DOI: 10.7554/eLife.08419

http://elifesciences.org/content/early/2015/11/19/eLife.08419