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domenica 24 dicembre 2017

# behav: a form of modified oxytocin (a molecule of love), with less adverse effects

<< Oxytocin is clinically used to induce labor, and there is interest in using this peptide to treat social disorders. However, oxytocin triggers adverse cardiovascular side effects  >>

AA << generated ligands based on oxytocin with subtle modifications >>

this new molecular form << reduced social fear in mice and induced contractile activity in human myometrial strips without affecting cultured cardiomyocytes >>

Markus Muttenthaler, Asa Andersson, et al.  Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species. Sci. Signal.  2017; 10 (508): eaan3398. 10.1126/scisignal.aan3398. Dec 05, 2017.

http://stke.sciencemag.org/content/10/508/eaan3398

Scientists create molecule of love with less complications. Dec 12, 2017.

https://m.phys.org/news/2017-12-scientists-molecule-complications.html

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