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lunedì 8 aprile 2019

# epidem: silent invasions, the case of Candida auris.

<< Bacteria are rebelling  >>

<< The germ, a fungus called Candida auris, preys on people with weakened immune systems, and it is quietly spreading across the globe. >>

Matt Richtel,  Andrew Jacobs. DEADLY GERMS, LOST CURES. A Mysterious Infection, Spanning the Globe in a Climate of Secrecy. The rise of Candida auris embodies a serious and growing public health threat: drug-resistant germs. NYT. April 6, 2019.

https://www.nytimes.com/2019/04/06/health/drug-resistant-candida-auris.html

<< The recent rate of emergence of pathogenic fungi that are resistant to the limited number of commonly used antifungal agents is unprecedented. The azoles, for example, are used not only for human and animal health care and crop protection but also in antifouling coatings and timber preservation. The ubiquity and multiple uses of azoles have hastened the independent evolution of resistance in many environments. One consequence is an increasing risk in human health care from naturally occurring opportunistic fungal pathogens that have acquired resistance to this broad class of chemicals. >>

Matthew C. Fisher, Nichola J. Hawkins, et al.  Worldwide emergence of resistance to antifungal drugs challenges human health and food security. Science  May 18, 2018
Vol. 360, Issue 6390, pp. 739-742  doi: 10.1126/science.aap7999

http://science.sciencemag.org/content/360/6390/739

FonT

Per nostra - di noi umani - fortuna oggi si puo' analizzare, studiare ed eventualmente manipolare in modo fine il codice genetico di virus, batteri, etc. grazie alla tecnica CRISPR, tecnica a suo tempo (e per molto tempo) considerata di nessuna importanza da entita' di alta- altissima luminescenza ...

Eric S. Lander. The Heroes of CRISPR.
Cell. 14 January 2016, Vol.164(1): 18–28, doi:10.1016/j.cell.2015.12.041

http://www.sciencedirect.com/science/article/pii/S0092867415017055

Also: "CRISPR"

https://flashontrack.blogspot.com/search?q=crispr

https://www.ncbi.nlm.nih.gov/m/pubmed/?term=crispr

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