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martedì 6 ottobre 2020
# zoo: Tatupa, a random genus name for fixing a rare species of tropical Heteroptera with long antennas
giovedì 21 febbraio 2019
# zoo: the rehabilitation of insects: not all of them are pests
<< Insects are important wildlife often overlooked in urban habitats. What we do notice are the cockroaches, ants and mosquitoes in and around our homes. All too often we reach for the insect spray. >>
Lizzy Lowe, Cameron Webb, Manu Saunders, Tanya Latty. The battle against bugs: it’s time to end chemical warfare. Feb 17, 2019
https://theconversation.com/the-battle-against-bugs-its-time-to-end-chemical-warfare-111629
Also
https://flashontrack.blogspot.com/search?q=beetle
lunedì 3 settembre 2018
# gst: a chaos-inducing approach against superbugs evolution
<< The CHAOS [Controlled Hindrance of Adaptation of OrganismS] method takes advantage of this effect, pulling multiple genetic levers in order to build up stress on the bacterial cell and eventually trigger a cascading failure, leaving the bug more vulnerable to current treatments. The technique does not alter the bug's DNA itself, only the expression of individual genes, similar to the way a coded message is rendered useless without the proper decryption. >>
<< We now have a way to cut off the evolutionary pathways of some of the nastiest bugs and potentially prevent future bugs from emerging at all, >> Peter Otoupal
Chaos-inducing genetic approach stymies antibiotic-resistant superbugs. University of Colorado at Boulder. Sept 3, 2018.
https://m.phys.org/news/2018-09-chaos-inducing-genetic-approach-stymies-antibiotic-resistant.html
<< While individual perturbations improved fitness during antibiotic exposure, multiplexed perturbations caused large fitness loss in a significant epistatic fashion. >>
Peter B. Otoupal, William T. Cordell, et al. Multiplexed deactivated CRISPR-Cas9 gene expression perturbations deter bacterial adaptation by inducing negative epistasis. Comm Biol 1 (129) Sept 3, 2018
lunedì 27 agosto 2018
# drugs: proteins found in tick saliva (Rhipicephalus and Amblyomma) to treat a potentially fatal form of heart disease
<< Tick saliva contains proteins [evasins] that suppress chemokine-driven inflammation by binding and neutralizing multiple chemokines simultaneously, helping them to suck blood for several weeks without eliciting inflammation. >>
Kamayani Singh, Graham Davies, et al. Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine - binding activities. Scientific Reports. Jun 27, 2017; 7 (4267).
https://www.nature.com/articles/s41598-017-04378-1
AA << has identified several new tick evasins and shown that one of them, P991_AMBCA, from the cayenne tick found in the Americas, can bind to and block the effect of chemokines which cause inflammation in myocarditis, heart attack and stroke. >>
From bug to drug - tick saliva could be key to treating heart disease. University of Oxford. Jun 27, 2017.
https://m.phys.org/news/2017-06-bug-drugtick-saliva-key-heart.html
Also: "saliva" in:
mercoledì 1 febbraio 2017
# s-chem: a viscoelastic tongue with reversible saliva (spit and softness) to hang on to the next meal
<< A frog uses its whip-like tongue to snag its prey faster than a human can blink, hitting it with a force five times greater than gravity >>
<< A frog's saliva is thick and sticky during prey capture, then turns thin and watery as prey is removed inside the mouth >>
<< The tongue, which was found to be as soft as brain tissue and 10 times softer than a human's tongue, stretches and stores energy much like a spring >>
<< This combination of spit and softness is so effective that it provides the tongue 50 times greater work of adhesion than synthetic polymer materials such as sticky-hand toys >>
<< There are actually three phases (..) When the tongue first hits the insect, the saliva is almost like water and fills all the bug's crevices. Then, when the tongue snaps back, the saliva changes and becomes more viscous—thicker than honey, actually—gripping the insect for the ride back. The saliva turns watery again when the insect is sheared off inside the mouth >>
Reversible saliva allows frogs to hang on to next meal. Jan. 31, 2017
https://m.phys.org/news/2017-01-reversible-saliva-frogs-meal.html
Alexis C.Noel, Hao-Yuan Guo, et al. Frogs use a viscoelastic tongue and non-Newtonian saliva to catch prey. Journal of The Royal Society Interface. Publ. 1 February 2017. DOI: 10.1098/rsif.2016.0764
http://rsif.royalsocietypublishing.org/content/14/127/20160764