# s-chem: a strange allosteric regulation by volume fluctuations

<< a typical globular protein [the synaptic protein PSD-95] is able to undergo significant changes in volume under native conditions while exhibiting no additional changes in protein structure.These native state volume fluctuations were found to correlate with changes in internal motions that were previously recognized as a source of allosteric entropy. This finding offers a novel mechanistic basis for allostery in the absence of canonical structural change. >>

Anthony B. Law, Paul J. Sapienza, et al. Native State Volume Fluctuations in Proteins as a Mechanism for Dynamic Allostery. J. Am. Chem. Soc. 2017, 139 (10), pp 3599–3602 doi: 10.1021/jacs.6b12058

http://pubs.acs.org/doi/abs/10.1021/jacs.6b12058

Jeff  Hansen. 'Rosetta Stone' protein offers new mechanism  of allostery.  May 24, 2017

https://m.phys.org/news/2017-05-rosetta-stone-protein-mechanism-allostery.html

# s-phyto: the three ways of the plastoquinone inside the photosystem II complex

<< The surprise in this process was the seemingly uncoordinated way in which it happens. 'The idea in the field was that there were two channels through which plastoquinone could pass - one would be the entrance, the other the exit', says Marrink [Siewert J.  Marrink]. As it turned out, there were three channels which could all be used to enter or leave the complex. >>

<< Any plastoquinone molecules in the membrane would quickly enter the photosystem II (PSII) complex, but might leave it again without electrons, or hover around inside the complex for a while before finally binding in the exchange cavity, where it could accept electrons. Marrink: 'It is all very much dominated by entropy.' >>

University of Groningen. Molecular dynamics simulations reveal chaos in electron transport. ScienceDaily. 10 May 2017.

https://www.sciencedaily.com/releases/2017/05/170510075547.htm

Floris J. Van Eerden, Manuel N. Melo, et al. Exchange pathways of plastoquinone and plastoquinol in the photosystem II complex. Nature Communications 8, Article number: 15214 (2017) doi: 10.1038/ncomms15214

https://www.nature.com/articles/ncomms15214

FonT

<< Nature turned out to be less orderly than we had assumed >> afferma Siewert J.  Marrink. Percio' anche il classico vasetto della nonna contenente la classica piantina talvolta perfino stitichella, sarebbe testimonianza, per un aspetto decisamente peculiare,  fondamentale della sua normale fisiologia (la fotosintesi clorofilliana), di pulsatile motore caotico ...

# s-cell: to control living cells with a smartphone

<< The cells [live cells that can release insulin] were then embedded with tiny LED lights inside a hydrogel and transplanted under the skin of diabetic mice. And—get this—the entire system was controlled with a custom Android app, which remotely turns on the implanted LEDs and activates insulin-producing cells based on the level of circulating blood sugar levels. >>

Shelly Fan. These Cells Are Engineered to Be Controlled by a Smartphone. May 11, 2017.

https://singularityhub.com/2017/05/11/these-cells-are-engineered-to-be-controlled-by-a-smartphone/

<< With the increasingly dominant role of smartphones in our lives ... >>

Jiawei Shao, Shuai Xue, et al. Smartphone-controlled optogenetically engineered cells enable semiautomatic glucose homeostasis in diabetic mice. Science Translat Med  26 Apr 2017: Vol. 9, Issue 387, eaal2298
DOI: 10.1126/scitranslmed.aal2298

http://stm.sciencemag.org/content/9/387/eaal2298

# s-gst: controlling light-harvesting in molecular ensembles

AA << propose that the trap is a Frenkel exciton state formed much below the main exciton band edge due to an environmentally induced heavy-tailed Lévy disorder. This points to disorder engineering as a new avenue in controlling light-harvesting in molecular ensembles >>

Merdasa A, Jiménez Á, et al. Single
Lévy states-disorder induced energy funnels in molecular aggregates. Nano Lett. 2014 Dec 10;14(12):6774-81. doi: 10.1021/nl5021188. Epub 2014 Nov 7. PubMed PMID:
25349900.

http://pubs.acs.org/doi/abs/10.1021/nl5021188

also

"Frenkel exciton state" in:

https://journals.aps.org/search/

https://arxiv.org/find/all/1/all:+AND+state+AND+Frenkel+exciton/0/1/0/all/0/1

# n-soc: prospettiche meta- geometriche meta- fusioni, by Cedric

<< quelli (i requisiti) sono solo la precondizione, il bello viene adesso >> Cedric Villani.

Stefano Montefiori. Francia, il  candidato matematico «Uniremo elite e popolo» Cedric  Villani  alle  politiche  con  «En  Marche»

http://www.corriere.it/esteri/17_maggio_18/candidato-matematico-il-bello-viene-adessouniremo-elite-popolo-f5398c92-3b3d-11e7-935a-b58ef33c02e7.shtml

FonT

questo post meriterebbe una rima (quasistocastica senz'altro [inkpi.blogspot.it]) ma sembrerebbe  sparare con tromboncino armato di katyusha contro una postazione di pazienti di Medici Senza Frontiere, percio' mi astengo ...

# s-gst: emerging mixed-dimensional weak heterostructures

<< The isolation of a growing number of two-dimensional (2D) materials has inspired worldwide efforts to integrate distinct 2D materials into van der Waals (vdW) heterostructures >>

<< the vdW heterostructure concept can be extended to include the integration of 2D materials with non-2D materials that adhere primarily through non-covalent interactions >>

Deep Jariwala, Tobin J. Marks & Mark C. Hersam.  Mixed-dimensional van der Waals heterostructures. Nature Materials 16, 170–181 (2017) doi:10.1038/nmat4703.

https://www.nature.com/nmat/journal/v16/n2/full/nmat4703.html

FonT

teoria dei sistemi prevede, senz'altro in prima approx, il trasferimento, l'esportazione di concetti e modelli tra differenti contesti, anche lontani tra loro ...

cfr:  Ludwig von Bertalanffy. General System Theory (1969). Teoria generale dei sistemi. Arnoldo Mondadori Editore SpA Milano (1983).

https://it.m.wikipedia.org/wiki/Ludwig_von_Bertalanffy

# n-lang: this is not a question of grammatical punctiliousness; time as a container to be filled

<< Shortest versus smallest isn’t actually a question of grammatical punctiliousness. Different languages frame time differently. Swedish and English speakers, for example, tend to think of time in terms of distance—what a long day, we say. Time becomes an expanse one has to traverse. Spanish and Greek speakers, on the other hand, tend to think of time in terms of volume—what a full day, they exclaim. Time becomes a container to be filled >>

Kendra Pierre-Louis. The language you speak changes your perception of time. TIME  IS  RELATIVE. May 9, 2017.

http://www.popsci.com/language-time-perception

<< These results reveal the malleable nature of human time representation as part of a highly adaptive information processing system >>

Bylund  E , Athanasopoulos  P. The Whorfian Time Warp: Representing Duration Through  the Language Hourglass. J  Exp  Psychol  Gen. 2017  Apr  27.  doi:  10.1037/xge0000314.

https://www.ncbi.nlm.nih.gov/pubmed/28447839