# brain: collective dynamics in spiking neural networks beyond Dale's principle.

<< ️Dale's Principle has historically guided neuroscience research as a valuable rule of thumb, namely that all synapses on each neuron release the same set of neurotransmitters. Most existing Spiking Neuron Network models share this dichotomous assumption that neurons are either excitatory or inhibitory; however, recent experimental evidence points towards co-release mechanisms that violate this assumption. >>

<< ️Here, (AA) introduce a minimal model of "Bilingual" neurons violating Dale's principle that can exert both excitatory and inhibitory effects. (They) identify parameter regimes in which this architecture exhibits transitions between synchronous and asynchronous dynamics that differ quantitatively from those observed in a matched monolingual control architecture. >>

<< ️(AA) report distinct information-processing signatures both at the level of neurons and higher-order interactions between them near the phase transitions. These (AA) results suggest that the population of neurons violating Dale's principle may provide an alternative mechanism for regulating large-scale oscillatory activity in neural circuits. >>

Ross Ah-Weng, Hardik Rajpal. Collective Dynamics in Spiking Neural Networks Beyond Dale's Principle. arXiv: 2602.23202v1 [q-bio.NC]. Feb 26, 2026.

https://arxiv.org/abs/2602.23202

Also: brain, neuro, network, transition, in https://www.inkgmr.net/kwrds.html 

Keywords: gst, brain, neuro, networks, transitions, neural circuits, spiking neuron networks, excitatory and inhibitory effects, Dale's principle, Henry Hallett Dale, bilingual neurons, transitions between synchronous and asynchronous dynamics.