# brain: hippocampus can rewires itself even after a single experience.

<< ️Understanding how brains learn and remember remains among the most important challenges in science. Recent studies in the hippocampus implicate a new form of synaptic plasticity, named behavioral timescale synaptic plasticity (BTSP), in the generation of experience-based learning and memory. BTSP is a strong, bidirectional type of plasticity that affects synaptic weights over many seconds of time. It is induced by single dendritic plateau potentials, as opposed to many action potentials, and is thus capable of producing new place cells in one trial. Plateau potential initiation is controlled, at least in part, by local feedback inhibition and an instructive input from a higher-order brain region that potentially links the plasticity to current experience.  >>

<< ️The new credit assignment procedure in BTSP provides a nonstandard mechanism for memory storage and retrieval that could mitigate the need for widespread synapse stabilization. In addition, it may allow hippocampal networks both to form memories of specific behavioral episodes and to generalize on the basis of past episodes. Finally, recent BTSP investigations could provide a basis for future explorations into how brains learn and remember, ranging from the systems and cognitive levels down to the basic biochemical building blocks of learning and memory. >>

Jeffrey C. Magee. Behavioral timescale synaptic plasticity: properties, elements and functions. Nature Neurosci 29; 520–534. Feb 20, 2026.

https://www.nature.com/articles/s41593-026-02214-2

Antoine D. Madar, Aaron D. Milstein, Thomas J. O’Dell, et al. Behavioral Timescale Synaptic Plasticity: A Burst in the Field of Learning and Memory. J. Neurosci .45 (46) e1332252025. Nov 12,  2025.

https://www.jneurosci.org/content/45/46/e1332252025

Yasemin Saplakoglu. A New Type of Neuroplasticity Rewires the Brain After a Single Experience. quantamagazine.org. Apr 24, 2026.

https://www.quantamagazine.org/a-new-type-of-neuroplasticity-rewires-the-brain-after-a-single-experience-20260424/

Also: brain, dance, in https://www.inkgmr.net/kwrds.html 

Keywords: brain, dance,  hippocampus, synaptic plasticity, behavioral timescale synaptic plasticity (BTSP), learning, memory, single dendritic plateau potentials, local feedback inhibition.