Translate

Visualizzazione post con etichetta psilocybin. Mostra tutti i post
Visualizzazione post con etichetta psilocybin. Mostra tutti i post

martedì 10 maggio 2022

# brain: waiting for 'magic strings', psilocybin is a 'relatively safe' drug.

<< Psilocybin-containing mushrooms are used for recreational, spiritual, self-development and therapeutic purposes. However, physiologically relatively nontoxic, adverse reactions are occasionally reported. >>

The << study investigated the 12-month prevalence and nature of magic mushroom-related adverse reactions resulting in emergency medical treatment seeking in a global sample of (9.233) people reporting magic mushroom use. >>️
<< The results confirm psilocybin mushrooms are a relatively safe drug, with serious incidents rare and short lasting. Providing harm-reduction information likely plays a key role in preventing adverse effects. More research is needed to examine the detailed circumstances and predictors of adverse reactions including rarer physiological reactions. >>️

Emma I Kopra, Jason A Ferris, et al. Adverse experiences resulting in emergency medical treatment seeking following the use of magic mushrooms. Journal of Psychopharmacology. 1-9. doi: 10.1177/ 02698811221084063. 
Apr 7, 2022.


<< Psilocybin is currently being investigated in clinical trials for mental health conditions across the world, including in our department, (..) It is important to draw a distinction between the use of psilocybin in clinical or research settings and recreational magic mushroom use, with partly overlapping yet distinct safety considerations and risk profiles. >> Emma Kopra. 

Beth Ellwood. Large survey suggests psilocybin is a “relatively safe” drug, with serious reactions being rare and short-lived. May 4, 2022. 


Also

keyword 'magic string' in FonT


keyword 'psychedelic' in FonT


Keywords: brain, drugs, magic string, magic mushrooms, psilocybin, psychedelic


lunedì 30 dicembre 2019

# pharma: a 'magical' (engineered) Escherichia coli to produce psychedelic psilocybin

<< Psilocybin, the prodrug of the psychoactive molecule psilocin, has demonstrated promising results in clinical trials for the treatment of addiction, depression, and post-traumatic stress disorder.  >>

AA << present the development of a modular biosynthetic production platform in the model microbe, Escherichia coli. (..) This is the highest psilocybin titer achieved to date from a recombinant organism and a significant step towards demonstrating the feasibility of industrial production of biologically-derived psilocybin. >>

Alexandra M.Adams, Nicholas A.Kaplan, et al. In vivo production of psilocybin in E. coli. Metabolic Engineering. Volume 56, pages 111-9. doi: 10.1016/j.ymben.2019.09.009. Sep 21, 2019.

https://www.sciencedirect.com/science/article/pii/S109671761930309X

Tanya Lewis. E. coli Could Produce a Popular Psychedelic for Therapeutic Use. Scientists engineered the bacterium to produce psilocybin. SCIAM. 322, 1, 16. Jan 2020.

https://www.scientificamerican.com/article/e-coli-could-produce-a-popular-psychedelic-for-therapeutic-use/

Also

keyword 'magic' in FonT

https://flashontrack.blogspot.com/search?q=magic