AA << captured highly transient interactions between transcription factors-proteins that control gene expression-and target genes in the genome and showed that these typically missed interactions have important practical implications. >>
<< Our approaches to capturing transient transcription factor-target interactions genome-wide can be applied to validate dynamic interactions of transcription factors for any pathway of interest in agriculture or medicine, >> Gloria Coruzzi.
Biologists capture fleeting interactions between regulatory proteins and their genome-wide targets. New York University. Mar 2, 2020.
https://m.phys.org/news/2020-03-biologists-capture-fleeting-interactions-regulatory.html
José M. Alvarez, Anna-Lena Schinke, et al. Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade. Nat Commun 11, 1157. doi: 10.1038/s41467-020-14979-6. Mar 2, 2020
https://www.nature.com/articles/s41467-020-14979-6
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