<< A bacterial genome’s evolution under changing drug concentrations displays effects of memory formation and mimics how disordered solids respond to external forces. >>️
AA << simulate the effect on adaptation of an environment that is constantly changing. Using a model that describes how slow-moving disordered systems respond to external forces, (they) find that microbe evolution in changing drug concentrations exhibits hysteresis and memory formation. They use analytical methods and numerical simulations to connect these statistical physics concepts to bacterial drug resistance. >>️
AA << find that this behavior mimics that of disordered systems driven by external forces, such as ferromagnetic materials subjected to magnetic fields or amorphous materials subjected to a shearing force. They say that while their approach focuses on the evolution of drug resistance, the framework can be adapted to other problems in evolutionary biology that involve changing environmental parameters. >>
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Rachel Berkowitz. Disordered Systems Mimic Genetic Evolution. Physics 15, s118. Sep 20, 2022.
Suman G. Das, Joachim Krug, Muhittin Mungan. Driven Disordered Systems Approach to Biological Evolution in Changing Environments. Phys. Rev. X 12, 031040. Sep 20, 2022.
Also
keyword 'disorder' in FonT
keyword 'disordine' in Notes
(quasi-stochastic poetry)
Keywords: gst, disorder, disordered systems, evolution, genetic evolution
