# astro: you might find erratic massive black holes in dwarf galaxies ...

<< The new VLA (Very Large Array) observations revealed that 13 of these galaxies have strong evidence for a massive black hole that is actively consuming surrounding material. (AA) were very surprised to find that, in roughly half of those 13 galaxies, the black hole is not at the center of the galaxy, unlike the case in larger galaxies, >>  Amy Reines.

<< The scientists said this indicates that the galaxies likely have merged with others earlier in their history. This is consistent with computer simulations predicting that roughly half of the massive black holes in dwarf galaxies will be found wandering in the outskirts of their galaxies. >>

<< This work has taught us that we must broaden our searches for massive black holes in dwarf galaxies beyond their centers to get a more complete understanding of the population and learn what mechanisms helped form the first massive black holes in the early Universe, >> Amy Reines.

Astronomers find wandering massive black holes in dwarf galaxies. National Radio Astronomy Observatory. Jan 6, 2020.

https://m.phys.org/news/2020-01-astronomers-massive-black-holes-dwarf.html    

Amy Reines, James Condon, et al. A New Sample of (Wandering) Massive Black Holes in Dwarf Galaxies from High Resolution Radio Observations. arXiv:1909.04670v1 [astro-ph.GA] Sep 10, 2019.

https://arxiv.org/abs/1909.04670

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# gst: apropos of 'large deviations', the instanton, to trace rogue waves

<< Strong evidence is given that the rogue waves observed in the tank are hydrodynamic instantons, that is, saddle point configurations of the action associated with the stochastic model of the wave system. (..) these hydrodynamic instantons are complex spatiotemporal wave field configurations which can be defined using the mathematical framework of large deviation theory and calculated via tailored numerical methods. These results indicate that the instantons describe equally well rogue waves created by simple linear superposition (in weakly nonlinear conditions) or by nonlinear focusing (in strongly nonlinear conditions), paving the way for the development of a unified explanation to rogue wave formation. >>

Giovanni Dematteis, Tobias Grafke, et al. Experimental Evidence of Hydrodynamic Instantons: The Universal Route to Rogue Waves. Phys. Rev. X 9, 041057. Dec 18, 2019.

https://journals.aps.org/prx/abstract/10.1103/PhysRevX.9.041057

Stefano Trillo, Amin Chabchoub. Viewpoint: A Unifying Framework for Describing Rogue Waves. Physics 12, 146. Dec18, 2019.

https://physics.aps.org/articles/v12/146

# life: apropos of fake news, creation of misinformation, and how misinformation can spread via person-to-person communication.

<< Numerical facts play a prominent role in public discourse, but individuals often provide incorrect estimates of policy-relevant numerical quantities >>

Jason C Coronel, Shannon Poulsen, Matthew D Sweitzer.  Investigating the generation and spread of numerical misinformation: A combined eye movement monitoring and social transmission approach. Human Communication Research, hqz012, doi: 10.1093/hcr/hqz012. Dec 5, 2019

https://academic.oup.com/hcr/advance-article-abstract/doi/10.1093/hcr/hqz012/5652186

<< If you're looking for who's responsible for all the misinformation out there, you might want to take a peek in the mirror. >>

Jennifer Smola. Facts are misremembered to fit personal biases, study finds.  The Columbus Dispatch (Columbus, Ohio). Dec 26, 2019.

https://phys.org/news/2019-12-facts-misremembered-personal-biases.html

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fake news, by slow or/and fast catalysis, everyday, everywhere, in all ages. Feb 20, 2017.  

https://flashontrack.blogspot.com/2017/02/n-soc-fake-news-by-slow-orand-fast.html

<< qui non e' impossibile immaginare una entita' di intelligenza artificiale (AI) che, in modalita' autonoma, intenda utilizzare "le immagini" di uno scenario in transizione di questo tipo come modello base di prima approx per l'analisi del comportamento e le previsioni all'interno di un sistema costituito da entita' altre ... ad es. all'interno di un  contesto culturale umano; >>

Anomalous formation of molecules after vapor deposition.  Dec 31, 2015.

https://flashontrack.blogspot.com/2015/12/rmx-s-gst-anomalous-formation-of.html

<< Il ruolo sociale del pettegolezzo e' immenso. [..] Il pettegolezzo e' una inquisizione continua e reciproca, uno spionaggio e una sorveglianza di tutti da parte di tutti, a tutte le ore del giorno e della notte. >>

Tarde, Gabriel. Ecrits de psychologie sociale. Cit. Prigogine, Ilya. La Nuova Alleanza. Milano: Longanesi & C., 1979,  pp.147-149. Trad. Morchio, Renzo.

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# life: apropos of transient dynamics, a predator–prey system seems to long-term survive without self-destruction

<< Predator-prey cycles rank among the most fundamental concepts in ecology, are predicted by the simplest ecological models and enable, theoretically, the indefinite persistence of predator and prey. However, it remains an open question for how long cyclic dynamics can be self-sustained in real communities.  >>

Bernd Blasius, Lars Rudolf, et al. Long-term cyclic persistence in an experimental predator–prey system. Nature doi:10.1038/s41586-019-1857-0. Dec 18, 2019.

https://www.nature.com/articles/s41586-019-1857-0

<<  It will be important to bring together this work (..) with theoretical models that are currently being developed. Doing so should provide more insights into the role of transient dynamics in natural systems. >>

Long-term predator–prey cycles finally achieved in the lab. Nature. doi: 10.1038/d41586-019-03603-3. Dec 18, 2019

https://www.nature.com/articles/d41586-019-03603-3

# gst: the emergence of a phase transition during asynchronous neural activities

<< The activity of a sparse network of leaky integrate-and-fire neurons is carefully revisited with reference to a regime of a bona-fide asynchronous dynamics. (..) The comparison between quenched and annealed (i.e. in setups where the synaptic connections are continuously randomly reshuffled) networks reveals the emergence of substantial differences when the coupling strength is increased, via a scenario somehow reminiscent of a phase transition. >>

Ekkehard Ullner, Antonio Politi, Alessandro Torcini. Quantitative and qualitative analysis of asynchronous neural activity. arXiv:1912.09207v1 [q-bio.NC]. Dec 19, 2019. 

https://arxiv.org/abs/1912.09207

# brain: the memory switch p75NTR

<< many molecular and environmental factors have been studied to understand how synaptic plasticity is modulated. Sleep, as an evolutionary conserved biological function, has shown to be a critical player for the consolidation and filtering of synaptic circuitry underlying memory traces. Although sleep disturbances do not alter normal memory consolidation, they may reflect fundamental circuit malfunctions that can play a significant role in exacerbating diseases, such as autism and Alzheimer's disease. (..) This paper will review the role of the p75NTR (p75 neurotrophic receptor), critically discuss the impact and implications of this research as the bridge for sleep research and neurological diseases.>>

Shen Ning, Mehdi Jorfi. p75NTR as a Molecular Memory Switch.  arXiv: 1912.11449v1 [q-bio.NC]. Dec 24, 2019.

https://arxiv.org/abs/1912.11449

# pharma: a 'magical' (engineered) Escherichia coli to produce psychedelic psilocybin

<< Psilocybin, the prodrug of the psychoactive molecule psilocin, has demonstrated promising results in clinical trials for the treatment of addiction, depression, and post-traumatic stress disorder.  >>

AA << present the development of a modular biosynthetic production platform in the model microbe, Escherichia coli. (..) This is the highest psilocybin titer achieved to date from a recombinant organism and a significant step towards demonstrating the feasibility of industrial production of biologically-derived psilocybin. >>

Alexandra M.Adams, Nicholas A.Kaplan, et al. In vivo production of psilocybin in E. coli. Metabolic Engineering. Volume 56, pages 111-9. doi: 10.1016/j.ymben.2019.09.009. Sep 21, 2019.

https://www.sciencedirect.com/science/article/pii/S109671761930309X

Tanya Lewis. E. coli Could Produce a Popular Psychedelic for Therapeutic Use. Scientists engineered the bacterium to produce psilocybin. SCIAM. 322, 1, 16. Jan 2020.

https://www.scientificamerican.com/article/e-coli-could-produce-a-popular-psychedelic-for-therapeutic-use/

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