# brain: flies, mice and humans, comparable behaviors for balance and motor control

<< Comparative developmental genetics indicate insect and mammalian forebrains form and function in comparable ways. However, these data are open to opposing interpretations that advocate either a single origin of the brain and its adaptive modification during animal evolution; or multiple, independent origins of the many different brains present in extant Bilateria. Here, (AA) describe conserved regulatory elements that mediate the spatiotemporal expression of developmental control genes directing the formation and function of midbrain circuits in flies, mice, and humans. These circuits develop from corresponding midbrain-hindbrain boundary regions and regulate comparable behaviors for balance and motor control. (They) findings suggest that conserved regulatory mechanisms specify cephalic circuits for sensory integration and coordinated behavior common to all animals that possess a brain. >>

Jessika C. Bridi, Zoe N. Ludlow, et al. Ancestral regulatory mechanisms specify conserved midbrain circuitry in arthropods and vertebrates. PNAS. doi: 10.1073/ pnas.1918797117. Aug 3, 2020.

https://www.pnas.org/content/early/2020/07/31/1918797117  

Humans and flies employ very similar mechanisms for brain development and function. King's College London.  Aug 3, 2020.

https://phys.org/news/2020-08-humans-flies-similar-mechanisms-brain.html

Also

'mosca in bottiglia' in: 2066 - voli a casaccio. Notes. Oct 01, 2006.   (quasi-stochastic poetry)

https://inkpi.blogspot.com/2006/10/2066-voli-casaccio.html

Also

keyword 'flies' in FonT

https://flashontrack.blogspot.com/search?q=flies

# astro: runaway cooling of intracluster gas during a silent black hole

<< supermassive black holes play a fundamental role in regulating the formation of stars throughout cosmic time. This has been clearly demonstrated in the case of galaxy clusters in which powerful feedback from the central black hole is  preventing the hot intracluster gas from cooling catastrophically, thus reducing the expected star formation rates by orders of magnitude. >>

AA << present the first observational evidence for massive, runaway cooling occurring in the absence of supermassive black hole feedback in the high-redshift galaxy cluster SpARCS104922.6+564032.5 (..) The hot intracluster gas appears to be fueling a massive burst of star formation >>

<< Intracluster stars are therefore not only produced by tidal stripping and the disruption of cluster galaxies, but can also be produced by runaway cooling of hot intracluster gas at early times. Overall, these observations show the dramatic impact when supermassive black hole feedback fails to operate in clusters. They indicate that in the highest overdensities such as clusters and proto-clusters, runaway cooling may be a new and important mechanism for fueling massive bursts of star formation in the early universe. >>

J. Hlavacek-Larrondo, C.L. Rhea, et al. Evidence of runaway gas cooling in the absence of supermassive black hole feedback at the epoch of cluster formation. arXiv:2007.15660v1 [astro-ph.GA]. Jul 30, 2020.

https://arxiv.org/abs/2007.15660   

<< It reminds me of the old expression of 'when the cat's away, the mice will play,' (..) Here the cat, or black hole, is quiet and the mice, or stars, are very busy. >> Julie Hlavacek

Black hole fails to do its job. Chandra X-ray Center. Aug 3, 2020. 

https://phys.org/news/2020-08-black-hole-job.html   

# GST: how to harvest energy from impacting droplets

AA << designed an electrical generator that can harvest energy from impacting droplets and other sources of mechanical energy. (..) The electrical generator can be explained as being a permanently charged capacitor, also known as an electret. >>

They << managed to convert 11.8% of the mechanical energy of an impacting droplet into electrical energy, which is a significant improvement compared to the efficiency of similar devices. Furthermore, they demonstrated that the energy harvesting efficiency does not degrade after 100 days, requiring only a single 15 minute charging cycle before long-term application. >>

K.W. Wesselink. Generator developed for harvesting energy from droplets. 

University of Twente. Jul 8, 2020.

https://phys.org/news/2020-07-harvesting-energy-droplets.html

Hao Wu, Niels Mendel, et al. Charge Trapping‐Based Electricity Generator (CTEG): An Ultrarobust and High Efficiency Nanogenerator for Energy Harvesting from Water Droplets. Advanced Materials. doi: 10.1002/ adma.202001699. July 6, 2020.

https://onlinelibrary.wiley.com/doi/full/10.1002/adma.202001699  

Hao Wu, Niels Mendel, et al. Energy harvesting from drops impacting onto charged surfaces. Phys. Rev. Lett. Jun 25, 2020.

https://journals.aps.org/prl/accepted/ec07bYb0D261277cc08a6414c57b4ce4ab3e8da4f

Also

keyword 'drops' in Font:

https://flashontrack.blogspot.com/search?q=drops

# GST: apropos of the search of anomalies

<< I think in many respects, anomalies are a good driver of scientific creativity,  It’s like a paradox; you have to resolve it >> David Ireland

<< Anomalies force experimentalists to find ways of reducing systematic uncertainties, analyzing their data, and conducting more precise searches. Theorists, meanwhile, must grapple with anomalous results by building models that often assume new (..), >>

<< Particle physicists are faced with a growing list of “anomalies” — experimental results that conflict with the standard model but fail to overturn it for lack of sufficient evidence. >>

Dan Garisto. The Era of Anomalies. Physics 13, 79. May 14, 2020.

https://physics.aps.org/articles/v13/79

# gst: controlling particles with sound waves

<< Contactless manipulation of particles and cells using sound radiation forces that can be tuned and adjusted in real time has become important in various applications  (display tech, biomed sensors, imaging devices, diagnostic tools) >>

AA << use phononic crystals to tune sound fields in a microfluidic channel for controllable manipulation of microparticles and cells. An arbitrary stop-and-go motion of particles and cells along a predefined path in the channel is experimentally demonstrated. >>

Fei Li, Feiyan Cai, et al.  Phononic-Crystal-Enabled Dynamic Manipulation of Microparticles and Cells in an Acoustofluidic Channel.  Phys. Rev. Applied 13, 044077. Apr 30, 2020.

https://journals.aps.org/prapplied/abstract/10.1103/PhysRevApplied.13.044077

Controlling Particle Movements with Sound Waves. Physics 13, s58. Apr 30, 2020.

https://physics.aps.org/articles/v13/s58

# gst: a simple signal to drive complex dynamics

<< a developmental signaling pattern can be erased and replaced with a synthetic, patterned stimulus. (..) unlike pharmacological or genetic perturbations, light can be applied and removed quickly, focused with high spatial precision, or shaped into arbitrary spatial patterns. (AA) found that a simple all-or-none blue light stimulus, delivered to the embryonic termini, is sufficient to convert a lethal loss-of-function phenotype to rescue the full Drosophila life cycle: embryogenesis; larval development; pupation; adulthood; and fecundity. >>

<<  Such optical control over development could be used to probe cell and tissue-level regulation, engineer tissue organization, and correct developmental defects. >>

Heath E. Johnson, Nareg J.V. Djabrayan, et al. Optogenetic Rescue of a Patterning Mutant. Current Biology. 30, 1-11. doi: 10.1016/ j.cub.2020.06.059. Jul 23, 2020. 

https://www.sciencedirect.com/science/article/abs/pii/S0960982220309118

Complex developmental patterns are under the control of surprisingly simple signals. Princeton University. Jul 23, 2020.

https://phys.org/news/2020-07-complex-developmental-patterns-surprisingly-simple.html   

Also

keyword 'signal' in FonT

https://flashontrack.blogspot.com/search?q=signal

keyword 'signal' in Notes (quasi-stochastic poetry)

https://inkpi.blogspot.com/search?q=signal

# life: high traffic, busy skies; every 6 months the Agency will publish news about TicTac Entities, UFOs, UAPs, ...

<< The Pentagon’s secretive UFO unit is going to make some of its findings public, The New York Times reported. And one consultant to the agency (Eric W. Davis, Astrophysicist) has briefed Defense Department officials of some highly unusual discoveries ― including items retrieved from “off-world vehicles not made on this Earth,” the newspaper said. >>

<< The military’s encounters with possible UFOs have come under intense interest since several videos were leaked in 2017 showing encounters with fast-moving objects including one given the nickname “Tic Tac” because it looked like one of the candies. This object, still not publicly identified, dropped from 60,000 feet to just 50 feet in a matter of seconds: “The part that drew our attention was how it wasn’t behaving within the normal laws of physics,” >> Chad Underwood, pilot. 

Ed Mazza. Explosive UFO Report In NYT Mentions ‘Off-World Vehicles Not Made On This Earth’. A Pentagon consultant made the revelation to The New York Times. Jul 24, 2020

https://m.huffpost.com/us/entry/us_5f1a5815c5b6296fbf404a07

<< It's not every day one reads a New York Times article containing the phrase “off-world vehicles not made on this earth". When I investigated UFOs for the UK government in the Nineties, I could only dream of such mainstream respectability for this subject. >> Nick Pope. 07:33 Jul 24, 2020. 

https://twitter.com/nickpopemod/status/1286534963597172736

Also

keyword 'ufo' in FonT:

https://flashontrack.blogspot.com/search?q=ufo

keyword 'ufo' in Notes (quasi-stochastic poetry):

https://inkpi.blogspot.com/search?q=ufo