# gene: bacteria and archaea CRISPR everywhere in nature

<< Single-celled bacteria and archaea use CRISPR systems to defend themselves against viruses known as bacteriophages. (..) Until now, researchers had identified six types of CRISPR system, designated I–VI. >>

AA << developed an algorithm called FLSHclust, which analyses genetic sequences in public databases. (..) By looking at the predicted function of the clusters, the researchers found around 130,000 genes associated in some way with CRISPR, 188 of which had never been seen before, >>️️

<< It’s a treasure trove for biochemists, >> Lennart Randau.

Sara Reardon. ‘Treasure trove’ of new CRISPR systems holds promise for genome editing. Nature. doi: 10.1038/ d41586-023-03697-w. Nov 23, 2023. 

https://www.nature.com/articles/d41586-023-03697-w

Han Altae-Tran, Soumya Kannan, Feng Zhang, et al. Uncovering the functional diversity of rare CRISPR-Cas systems with deep terascale clustering. 

Science, Vol 382, Issue 6673. doi: 10.1126/ science.adi1910. Nov 23, 2023. 

https://www.science.org/doi/10.1126/science.adi1910

Also: 'CRISPR' in https://flashontrack.blogspot.com/search?q=crispr  

Keywords: genome, gene, crispr, crispr system, ai, artificial intelligence