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mercoledì 7 febbraio 2024

# gst: feedback systems with switches that actuate after a preset delay.

AA << study the dynamics of a piecewise-linear second-order delay differential equation that is representative of feedback systems with relays (switches) that actuate after a fixed delay. The system under study exhibits strong multirhythmicity, the coexistence of many stable periodic solutions for the same values of the parameters. >>

AA << are able to show that slowly oscillating solutions are always stable if they exist. (They) also demonstrate the coexistence of stable periodic solutions with quasiperiodic solutions. >>

Lucas Illing, Pierce Ryan, Andreas Amann. ️Dynamics of a time-delayed relay system. Phys. Rev. E 109, 014223. Jan 23, 2024. 

Keywords: gst, feedback, relay, switch


sabato 3 febbraio 2024

# gst: transitions in disordered medium.

AA << study computationally the dynamics of forced, Brownian particles through a disordered system. As the concentration of mobile particles and/or fixed obstacles increase, (AA) characterize the different regimes of flow and address how clogging develops. >>️

AA << show that clogging is preceded by a wide region of anomalous transport, characterized by a power law decay of intermittent bursts. (..) this abnormal flow region is characterized by a coexistence between mobile and arrested particles, and their relative populations change smoothly as clogging is approached. >>
Sergi G. Leyva, Ignacio Pagonabarraga. Clogging transition and anomalous transport in driven suspensions in a disordered medium. Phys. Rev. E 109, 014618. Jan 31, 2024.


Also: transition, particledisorder, in https://www.inkgmr.net/kwrds.html

Keywords: gst, transition, particle, disorder


giovedì 1 febbraio 2024

# life: a new exception within the FDA Cures Act Informed Consent, the intriguing concept of 'Minimal Risk Clinical Investigations'.

<< The Food and Drug Administration (FDA, the Agency, or we) is issuing a final rule to amend its regulations to implement a provision of the 21st Century Cures Act (Cures Act). This final rule allows an exception from the requirement to obtain informed consent when a clinical investigation poses no more than minimal risk to the human subject and includes appropriate safeguards to protect the rights, safety, and welfare of human subjects. The final rule permits an institutional review board (IRB) to waive or alter certain informed consent elements or to waive the requirement to obtain informed consent, under limited conditions, for certain FDA-regulated minimal risk clinical investigations. >>️

Institutional Review Board Waiver or Alteration of Informed Consent for Minimal Risk Clinical Investigations. A Rule by the Food and Drug Administration on 12/21/2023. federalregister.gov 

FonT:  'Minimal Risk Clinical Investigations (MRCI)': here are intriguing both (i) the scientific formalization of the operational methods decided (case by case) by the FDA about MRCI and (ii) the possible strategies - if at least one exists - for avoiding the 'multitude of unaware' from this type of interception.

Also: Are you ready for all this?, in https://www.inkgmr.net/kwrds.html

Also: evitare (avoid), in Notes (quasi-stochastic poetry)  https://inkpi.blogspot.com/search?q=evitare


Also: Robert F. Kennedy's opinion on the issue https://twitter.com/RobertKennedyJr/status/1752126207821271080  

Keywords: life, FDA, informed consent, risk, minimal risk, minimal risk clinical investigations, avoidance, 1or2achoos, are you ready





martedì 30 gennaio 2024

# gst: analogy between quasi-2D and 3D liquid drops.

<< Liquid drops are everywhere around us and important in numerous technological applications. Here, (AA) demonstrate a quasi-two-dimensional (Q2D) analogy to the regular, often close to axisymmetric, three-dimensional (3D) drops. >>️

<< The Q2D drops are created by confining liquids between vertical walls, leading to formation of low aspect ratio capillary bridges that are deformed by gravity. When stationary, the Q2D drops adopt projected shapes that are analogous to 3D sessile drops, ranging from circular drops to puddles. >>️

<< When moving, the Q2D drops exhibit capillary and fluid mechanical behaviours analogous to 3D drops, including impacts and sliding on pseudo-surfaces. The Q2D drops also exhibit considerably more complex phenomena such as levitation, instabilities and pattern formation when subjected to external electric, magnetic and flow fields -- all seen also in regular 3D drops. >>️

<< 3D-Q2D analogy suggests that the diverse and often complicated phenomena observed in 3D drops can be studied in the Q2D geometry, >>
Tytti Kärki, Into Pääkkönen, et al. Quasi-Two-Dimensional Drops. arXiv: 2401.11845v1 [physics.flu-dyn]. Jan 22, 2024.

Also: drop, analogy, in https://www.inkgmr.net/kwrds.html

Keywords: gst, drop, droplet, droploid, analogy


sabato 27 gennaio 2024

# gst: intertwining order, disorder, and hierarchy


<< Nature hosts a wealth of materials showcasing intricate structures intertwining order, disorder, and hierarchy, delivering resilient multifunctionality surpassing perfect crystals or simplistic disordered materials. The engineering of such materials through nanoparticle assembly represents a burgeoning field, poised with potential to yield sustainable material systems rivaling or exceeding biological functionalities. >>

AA << review delineates the fundamental concept of complexity in the context of nanoscale materials. >>

Xiaoming Mao, Nicholas Kotov. Complexity, Disorder, and Functionality of Nanoscale Materials. arXiv: 2401.09567v1 [cond-mat.soft]. Jan 17, 2024. 

Also: nano, particle, order, disorder, in  https://www.inkgmr.net/kwrds.html

Keywords: nano, particle, order, disorder 




venerdì 26 gennaio 2024

# gst: compression and fracture of ordered and disordered droplet rafts

AA << simulate a two-dimensional array of droplets being compressed between two walls. The droplets are adhesive due to an attractive depletion force. As one wall moves toward the other, the droplet array is compressed and eventually induced to rearrange. The rearrangement occurs via a fracture, where depletion bonds are quickly broken between a subset of droplets. >>

<< For monodisperse, hexagonally ordered droplet arrays, this fracture is preceded by a maximum force exerted on the walls, which drops rapidly after the fracture occurs. >>

<< In small droplet arrays a fracture is a single well-defined event, but for larger droplet arrays, competing fractures can be observed. These are fractures nucleated nearly simultaneously in different locations. >>

AA << also study the compression of bidisperse droplet arrays. The addition of a second droplet size further disrupts fracture events, showing differences between ideal crystalline arrays, crystalline arrays with a small number of defects, and fully amorphous arrays. >>
Pablo Eduardo Illing, Jean-Christophe Ono-dit-Biot, et al. Compression and fracture of ordered and disordered droplet rafts. Phys. Rev. E 109, 014610. Jan 17, 2024.

Also: drop, defect, fracture, crack, in https://www.inkgmr.net/kwrds.html

randa (quasi-stochastic poetry) https://inkpi.blogspot.com/search?q=randa

Keywords: gst, drop, droplet, raft, defect, fracture, crack



giovedì 25 gennaio 2024

# behav: mechanics of fire ant rafts as an active self-healing membrane

<< The unique ability of fire ants to form a raft to survive flooding rain has enchanted biologists as well as researchers in other disciplines. (..) a three-dimensional aggregation of fire ants exhibits viscoelasticity with respect to external compression and shearing among numerous unusual mechanical properties. >>️

AA << study the ant raft in its natural form, i.e., composing no more than two layers. This allowed to focus on the cracks that are unique to membranes and see how their patterns are influenced by the fact that these ants are mobile and can self-repair the damage to keep their raft from disintegration. >>️

They << show that vertical and horizontal shaking can also prompt fire ants to aggregate.  (..)  the pull force expedites the alignment of fire ants, in analogy to the effect of an electric field on liquid crystal polymers. >>️

<< One major finding is that the raft can exhibit zero Poisson's ratio without resorting to specific geometry structures. This is enabled by the active recruitment of ants from the top layer to the bottom layer to keep the raft from disintegrating. >>️
Chung-Hao Chen, Ting-Heng Hsieh, et al. Formation and mechanics of fire ant rafts as an active self-healing membrane. Phys. Rev. E 109, 014607. Jan 9, 2024. 

David Ehrenstein. Material Properties of Fire-Ant Rafts. Physics 17, s5. Jan 9. 2024. 

randa (quasi-stochastic poetry) https://inkpi.blogspot.com/search?q=randa

Also: behav, behavior, in  https://www.inkgmr.net/kwrds.html

Keywords behavior, behaviour, ant, raft, self-healing