# pnei: brain motor and fear circuits regulate leukocytes during acute stress

<< The nervous and immune systems are intricately linked. Although psychological stress is known to modulate immune function, mechanistic pathways linking stress networks in the brain to peripheral leukocytes remain poorly understood. Here, (AA) show that distinct brain regions shape leukocyte distribution and function throughout the body during acute stress in mice. >>️

Poller, W.C., Downey, J., et al. Brain motor and fear circuits regulate leukocytes during acute stress. Nature. doi: 10.1038/ s41586-022-04890-z. May 30, 2022. 

https://www.nature.com/articles/s41586-022-04890-z

PNEI: Psycho-Neuro-Endocrine-Immunology  

https://pubmed.ncbi.nlm.nih.gov/?term=pnei

Also

Inchingolo G. Percezione dello stato di salute e leucociti in anziani ultraottantenni.   Atti 36 Congresso Nazionale Società Italiana di Gerontologia e Geriatria, Palermo, 7-10 Novembre 1991.   Giornale di Gerontologia 1991; XXXIX(11): 753.

https://sites.google.com/site/inkgmr2/papers

keyword 'pnei' | in FonT

https://flashontrack.blogspot.com/search?q=pnei

keyword 'pnei' | in Notes 

 (quasi-stochastic poetry)

https://inkpi.blogspot.com/search?q=pnei

Keywords: pnei, neuroimmunology, leukocytes, fear, stress, virus, viral infection, adaptation, adaptive immunity 

# game: in a iterated prisoner's dilemma scenario forgiveness turns out to be an adaptation

<< Prisoner’s dilemma is used to represent a range of real life phenomena such as economics, commerce, nature and wildlife. >>

<< Researchers working on iterated prisoner's dilemma (IPD) with limited memory inspected the outcome of different forgetting strategies in homogeneous environment, within which all agents adopt the same forgetting strategy at a time. In this work, with the intention to represent real life more realistically, (AA) improve existing forgetting strategies, offer new ones, and conduct experiments in heterogeneous environment that contains mixed agents and compare the results with previous research as well as homogeneous environment >>

<< in a more realistic environment consisting of all types of agents, in terms of both cooperation probabilities and forgetting strategies, agents who forget defectors consistently outperform other forgetting strategies for all memory ratio values. Moreover, the best performing defectors are also the ones that forget other defectors. In other words, agents who “forgive” defectors are the best performers. Hence, forgiveness is an adaptation. >>

FMC : Forget most cooperator first 

FMP : Forget most played first 

FMU : Forget most unpredictable first 

FR :  Forget randomly 

FLP : Forget least played first 

FMD : Forget most defector first 

Meliksah Turker, Haluk O. Bingol. Forgiveness is an Adaptation in Iterated Prisoner's Dilemma with Memory. arXiv:2112.07894v1 [cs.GT]. Dec 15, 2021

https://arxiv.org/abs/2112.07894

Also

keyword 'game' | 'tit-for-tat' in FonT

https://flashontrack.blogspot.com/search?q=game

https://flashontrack.blogspot.com/search?q=tit-for-tat

keyword 'game' | 'tit-for-tat' in Notes

(quasi-stochastic poetry)

https://inkpi.blogspot.com/search?q=game

https://inkpi.blogspot.com/search?q=tit-for-tat

Keywords: game, iterated prisoner's dilemma, forgiveness, adaptation

# ecol: when a predator could help his prey to adapt to an uncertain future (among the fly Iteomyia salicisverruca) ...

<< The loss of biodiversity is rewiring the web of life; however, it is uncertain how this will affect the ability of remaining populations to evolve and adapt to future environments. >>

AA << conducted a field experiment that either maintained a natural community of predators or removed all but one of the predators that was able to impose selection on a common prey. (They) found that the loss of predators acted to constrain prey evolution toward a particular combination of traits. Moreover, (they) found that the loss of predators could make it more difficult for prey to adapt to uncertain future environments. Taken together, (these) results suggest that the simplification of the web of life may constrain the adaptive potential of remaining populations. >>

Matthew A. Barbour, Christopher J. Greyson‐Gaito, et al. Loss of consumers constrains phenotypic evolution in the resulting food web. Evolution Letters. doi: 10.1002/ evl3.170. Apr 20, 2020. 

https://onlinelibrary.wiley.com/doi/full/10.1002/evl3.170

<< Thinking about the big picture, our study hints at a potential insidious side effect of extinctions, (..) The extinction of natural enemies may compromise the ability of remaining species to adapt and persist in an uncertain and changing world. If this is true, this would put many ecosystems at even greater risk than we currently realize. >> Matthew A. Barbour.

Predators help prey adapt to an uncertain future. University of Zurich. 

 May 4, 2020

https://phys.org/news/2020-05-predators-prey-uncertain-future.html

# gst: an approach to delay solitary states within complex networks

AA << present a technique to engineer solitary states by means of delayed links in a network of neural oscillators and in coupled chaotic maps. Solitary states are intriguing partial synchronization patterns, where a synchronized cluster coexists with solitary nodes displaced from this cluster and distributed randomly over the network. >>

<< It is shown that the extent of displacement and the position of solitary elements can be completely controlled by the choice (values) and positions (locations) of the incorporated delays, reshaping the delay engineered solitary states in the network. >>

Leonhard Schulen, Saptarshi Ghosh, et al. Delay engineered solitary states in complex networks. arXiv:1908.01295v1 [nlin.AO] Aug 4, 2019.

https://arxiv.org/abs/1908.01295