# life; the hypothesis of early treatment (at home) of the virus sars-cov-2

Figure 1 - Proposed maladaptive hyperinflammatory response to SARS-CoV-2 infection (Perico N, Cortinovis M, Suter F, Remuzzi G. (2022))

<< A few observational studies have tested NSAIDs [non-steroidal anti-inflammatory drugs] (especially  relatively selective COX-2 inhibitors), often as part of multipharmacological protocols, for early outpatient treatment of COVID-19. The findings from these studies are promising and point to a crucial role of NSAIDs for the at-home management of people with initial COVID-19 symptoms. >>

<< Celecoxib, ibuprofen, and nimesulide should be avoided in children younger than 12 years, whereas aspirin should be taken only under prescription and at the dose recommended by the family doctor. >>️

️

Norberto Perico, Monica Cortinovis, Fredy Suter, Giuseppe Remuzzi. Home as the new frontier for the treatment of COVID-19: the case for anti-inflammatory agents. The Lancet Infectious Diseases. doi: 10.1016/ S1473-3099(22)00433-9. Aug 25, 2022. 

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00433-9/fulltext

FonT

therefore the deadly infection by sars-cov-2 that has generated so much suffering,  pain, and dead everywhere it is recently hypothesized that it could easily be treated at home (an early treatment) with some success.

Also

keywords 'covid-19' and 'NSAIDs' in PubMed

https://pubmed.ncbi.nlm.nih.gov/?term=covid-19+NSAIDs&filter=datesearch.y_1

Also

aproposito di '1or2achoos' (da Wuhan (?)) ... FonT. Jul 13  2022.

https://flashontrack.blogspot.com/2022/07/life-aproposito-di-1or2achoos-da-wuhan.html

Keywords: virus, coronavirus,  sarscov2, 2019ncov, covid19, 1or2achoos

# gst: vortex solitons in twisted circular waveguide arrays.

AA << address the formation of topological states in twisted circular waveguide arrays and find that twisting leads to important differences of the fundamental properties of new vortex solitons with opposite topological charges that arise in the nonlinear regime. >>️

They << find that such system features the rare property that clockwise and counter-clockwise vortex states are nonequivalent. >>️

Liangwei Dong, Yaroslav V. Kartashov, et al. Vortex solitons in twisted circular waveguide arrays. arXiv:2208.05049v1 [physics.optics]. Aug 9, 2022.

https://arxiv.org/abs/2208.05049

Also

keyword 'solitons' in Font

https://flashontrack.blogspot.com/search?q=solitons

keyword 'vortex' in FonT

https://flashontrack.blogspot.com/search?q=vortex

keyword 'vortice' in Notes

 (quasi-stochastic poetry)

https://inkpi.blogspot.com/search?q=vortice

Keywords: gst, solitons, vortex,  clockwise vortex, counter-clockwise vortex, waves

# art: pictures of the floating world, a guide to making shadow puppets

<< Hiroshige (Utagawa Hiroshige) lived in the 19th century, the end of the classical period of ukiyo-e, the art of woodblock-printed “pictures of the floating world.” In that time he became one of the form’s last masters, having cultivated not just a high level of artistic skill but a formidable productivity. In total, Hiroshige produced more than 8,000 works. >>️

<< But his mastery encompassed more than the urban and rural landscapes of his homeland, as evidenced by this much humbler project: a set of omocha-e, or instructional pictures for children, explaining how to make shadow puppets. >>️

Hiroshige, Master of Japanese Woodblock Prints, Creates a Guide to Making Shadow Puppets for Children (1842). Art, History. Jul 6th, 2021. 

https://www.openculture.com/2021/07/hiroshige-shadow-puppets.html  

Utagawa Hiroshige. Art Institute of Chicago. 

https://www.artic.edu/artists/34946/utagawa-hiroshige

Also

keyword 'fluttuante' in Notes

(quasi-stochastic poetry)

https://inkpi.blogspot.com/search?q=fluttuante

keyword 'floating' in FonT

https://flashontrack.blogspot.com/search?q=floating

keyword 'onda' in Notes 

(quasi-stochastic poetry)

https://inkpi.blogspot.com/search?q=onda

keyword 'waves' in FonT

https://flashontrack.blogspot.com/search?q=waves

Keywords: arts, puppets, shadow puppets, floating worlds, waves

# gst: rare transitions in noisy net scenarios

AA << study small white noise perturbations of planar dynamical systems with heteroclinic networks in the limit of vanishing noise. (They)  show that the probabilities of transitions between various cells that the network tessellates the plane into decay as powers of the noise magnitude. (They) show that the most likely scenario for the realization of these rare transition events involves spending atypically long times in the neighborhoods of certain saddle points of the network. >>️

Yuri Bakhtin, Hong-Bin Chen, Zsolt Pajor-Gyulai. Rare transitions in noisy heteroclinic networks. arXiv: 2205.00326v1 [math.PR]. Apr 30, 2022.    https://arxiv.org/abs/2205.00326

Also

keyword 'noise'  in FonT 

https://flashontrack.blogspot.com/search?q=noise

keyword 'rumore'  in Notes

(quasi-stochastic poetry)

https://inkpi.blogspot.com/search?q=rumore

Keywords: gst, transitions, networks, heteroclinic networks, noise

# gst: how a synchronization could emerge from chaotic activities

<< Can we find order in chaos? Physicists have shown, for the first time that chaotic systems can synchronize due to stable structures that emerge from chaotic activity. These structures are known as fractals, shapes with patterns which repeat over and over again in different scales of the shape. As chaotic systems are being coupled, the fractal structures of the different systems will start to assimilate with each other, taking the same form, causing the systems to synchronize. >>️

<< If the systems are strongly coupled, the fractal structures of the two systems will eventually become identical, causing complete synchronization between the systems. These findings help us understand how synchronization and self-organization can emerge from systems that didn't have these properties to begin with, like chaotic systems and biological systems. >>️

Topological synchronization of chaotic systems. Bar-Ilan University. Apr 22, 2022. 

https://phys.org/news/2022-04-topological-synchronization-chaotic.html

<< chaotic synchronization has a specific trait in various systems, from continuous systems and discrete maps to high dimensional systems: synchronization initiates from the sparse areas of the attractor, and it creates what (AA) termed as the ‘zipper effect’, a distinctive pattern in the multifractal structure of the system that reveals the microscopic buildup of the synchronization process. >>️

Lahav, N., Sendina-Nadal, I., et al. Topological synchronization of chaotic systems. Sci Rep 12, 2508. doi: 10.1038/ s41598-022-06262-z. Feb 15, 2022. 

https://www.nature.com/articles/s41598-022-06262-z

Also

keyword 'self-assembly' in FonT

https://flashontrack.blogspot.com/search?q=self-assembly

Keywords: gst, self-assembly, self-organization, fractals, topological synchronization, zipper effect, chaos, chaotic systems

# gst: like steering a marble through a tilting labyrinth, randomness seems to quickly deliver specific outcomes.

<< According to the infinite monkey theorem, a monkey randomly hitting the keys of a typewriter will eventually write something worth reading—but it might take a few trillion years of trying. For those lacking the patience to wait, (AA)  now show that randomness can deliver specific outcomes much more quickly.  Simulating a 2D nanocluster of a dozen particles, (they) determine the temperature at which thermal fluctuations can most quickly rearrange those particles into a predetermined shape. They find that this time can be dramatically cut by applying an appropriate macroscopic force to the particles. >>

<< The duo also simulated nanoclusters that were subject to a macroscopic force field, for example, metallic nanoparticles in an electric field. Like steering a marble through a tilting labyrinth, they found the optimal global force to apply at each iteration such that the nanocluster navigated the space of possible configurations several orders of magnitude more quickly. >>️️

Marric Stephens. Rearranging Nanoclusters Using Randomness. Physics 15, s83. Jun 22, 2022. 

https://physics.aps.org/articles/v15/s83

Francesco Boccardo, Olivier Pierre-Louis. Controlling the Shape of Small Clusters with and without Macroscopic Fields. Phys. Rev. Lett. 128, 256102. Jun 22, 2022.  

https://journals.aps.org/prl/abstract/10.1103/PhysRevLett.128.256102

Also

keyword 'random' in FonT:

https://flashontrack.blogspot.com/search?q=random

keyword 'error' | 'fuzzy' | 'noise'  in FonT 

https://flashontrack.blogspot.com/search?q=error

https://flashontrack.blogspot.com/search?q=fuzzy

https://flashontrack.blogspot.com/search?q=noise

keywords 'errore' | 'errori' in Notes (quasi-stochastic poetry)

https://inkpi.blogspot.com/search?q=errore

https://inkpi.blogspot.com/search?q=errori

keywords 'jelly roll' in FonT

https://flashontrack.blogspot.com/search?q=jelly+roll

Keywords: gst, nano, nanocluster, fluctuations, randomness, noise

# gst: a rocking shadow dance: the broken disk.

AA << reveal a new phenomenon dubbed the "rocking shadow" effect that describes how disks in forming planetary systems are oriented, and how they move around their host star. The effect also gives clues as to how they might evolve with time. >>

<< Protoplanetary disks are often thought to be shaped like dinner plates—thin, round and flat. However, recent telescope images from the Atacama Large Millimeter/Submillimeter Array (ALMA) show that this is not always the case. Some of the disks seen by ALMA have shadows on them, where the part of the disk closest to the star blocks some of the stellar light and casts a shadow onto the outer part of the disk. From this shadow pattern, it can be inferred that the inner part of the disk is oriented completely differently to the outer part, in what is called a broken disk. >>️️

<< As the inner disk moved through the gravitational pull of the central star, the shadow it cast moved across the outer disk. But instead of the shadow pattern moving around the disk like a clock-hand as expected, it rocked back and forth with a see-saw-like motion. So although the inside disk kept turning in the same direction, its shadow looked like it was rocking forwards and backwards. >>

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Examining rocking shadows in protoplanetary disks. Royal Astronomical Society. Jul 15, 2022.

https://phys.org/news/2022-07-shadows-protoplanetary-disks.html

Rocking shadows in broken 

circumbinary discs. 

https://youtu.be/-0kAqc-sObY

The National Astronomy Meeting (NAM) 2022. The University of Warwick, 11th. Jul 15, 2022.

https://nam2022.org/

keywords: gst, astro, shadow, rocking shadow, broken disc