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martedì 10 maggio 2022

# brain: waiting for 'magic strings', psilocybin is a 'relatively safe' drug.

<< Psilocybin-containing mushrooms are used for recreational, spiritual, self-development and therapeutic purposes. However, physiologically relatively nontoxic, adverse reactions are occasionally reported. >>

The << study investigated the 12-month prevalence and nature of magic mushroom-related adverse reactions resulting in emergency medical treatment seeking in a global sample of (9.233) people reporting magic mushroom use. >>️
️
️ << The results confirm psilocybin mushrooms are a relatively safe drug, with serious incidents rare and short lasting. Providing harm-reduction information likely plays a key role in preventing adverse effects. More research is needed to examine the detailed circumstances and predictors of adverse reactions including rarer physiological reactions. >>️

Emma I Kopra, Jason A Ferris, et al. Adverse experiences resulting in emergency medical treatment seeking following the use of magic mushrooms. Journal of Psychopharmacology. 1-9. doi: 10.1177/ 02698811221084063. 
Apr 7, 2022.


<< Psilocybin is currently being investigated in clinical trials for mental health conditions across the world, including in our department, (..) It is important to draw a distinction between the use of psilocybin in clinical or research settings and recreational magic mushroom use, with partly overlapping yet distinct safety considerations and risk profiles. >> Emma Kopra. 

Beth Ellwood. Large survey suggests psilocybin is a “relatively safe” drug, with serious reactions being rare and short-lived. May 4, 2022. 


Also

keyword 'magic string' in FonT


keyword 'psychedelic' in FonT


Keywords: brain, drugs, magic string, magic mushrooms, psilocybin, psychedelic


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mercoledì 20 aprile 2022

# life: apropos of transitions, a leap from chemistry to biology, the hypothesis of self-assembling droplets, the 'droplet world'.


AA << identify conditions suitable for concurrent peptide generation and self-assembly, and (..) show how a proliferating peptide-based droplet could be created by using synthesised amino acid thioesters as prebiotic monomers. Oligopeptides generated from the monomers spontaneously formed droplets through liquid–liquid phase separation in water. The droplets underwent a steady growth–division cycle by periodic addition of monomers through autocatalytic self-reproduction. Heterogeneous enrichment of RNA and lipids within droplets enabled RNA to protect the droplet from dissolution by lipids. >>

Matsuo, M., Kurihara, K. Proliferating coacervate droplets as the missing link between chemistry and biology in the origins of life. Nat Commun 12, 5487. doi: 10.1038/ s41467-021-25530-6. Sep 24,  2021.


<< By constructing peptide droplets that proliferate with feeding on novel amino acid derivatives, we have experimentally elucidated the long-standing mystery of how prebiotic ancestors were able to proliferate and survive by selectively concentrating prebiotic chemicals, (..) Rather than an RNA world, we found that 'droplet world' may be a more accurate description, as our results suggest that droplets became evolvable molecular aggregates—one of which became our common ancestor. >> Muneyuki Matsuo.

Answering a century-old question on the origins of life. Hiroshima University. Sep 27, 2021. 


Also

keyword 'drop' | 'droplet' in FonT



keyword 'transition' in FonT


keyword 'transizione' in Notes (quasi-stochastic poetry): 


keywords: life, originsoflife, transitions, drop, droplet







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giovedì 14 aprile 2022

# life: a weird revisited from ethnomedicine inside an approach in epidemiology, the 'saliva healers' vs. 'herd immunity'.

(A) 
<< chiamati 'dottori della saliva' >>
️
A pain-suppressive effect. Notes (quasi-stochastic poetry). Nov 14, 2006.    


(B) 
Apropos of "herd immunity" ... FonT. Mar 16, 2020. 


(C) 
<< During 2020, most schools were never pro-actively closed to hinder virus spreading (with compulsory physical attendance required by law in Sweden and no option for distance or home learning)  >> 

<< Many elderly people were administered morphine instead of oxygen despite available supplies, effectively ending their lives. >>️

<< The Swedish Strategy was also influential abroad, and became an argument in other countries including, among others, the United States (US), United Kingdom (UK) and Australia, to loosen restrictions >>️ 

<< Supporters of the natural herd-immunity strategy promoted a widespread “controlled” spread in society, to obtain herd-immunity without vaccination >>️ 

<< Email conversations and statements from the State Epidemiologist and others show that they at least speculated on the use of children to acquire herd-immunity, while at the same time publicly claiming children played a negligible role in transmission and did not become ill >> 

<< During 2020, however, Sweden had ten times higher COVID-19 death rates compared with neighbouring Norway. >>️️
️
Nele Brusselaers, David Steadson, et al. Evaluation of science advice during the COVID-19 pandemic in Sweden. Humanit Soc Sci Commun 9, 91. doi: 10.1057/ s41599-022-01097-5. Mar 22, 2022.  


Also

keyword 'saliva' in Notes  (quasi-stochastic poetry)   


keyword 'saliva' in FonT   


keyword 'virus' | 'sars-cov-2' | 'sars' in FonT   




keyword 'virus' in Notes (quasi-stochastic poetry):


Also

(here a homemade mask with a pre  antiviral spray mixture)

A funky, immediate approach of the sneezing from Wuhan (a relative safe barrier - this device is NOT a filter). FonT. Mar 20, 2020. 


keywords: ethnomedicine, saliva, saliva healers, herd immunity, virus, coronavirus, sars, mers, 2019ncov, sarscov2, covid19, 1or2achoos 








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martedì 12 aprile 2022

# life: bizarre RAG-time scenarios revisited in and around Paris

bizarre RAG-time scenarios revisited in and around Paris ... 

- Emmanuel Macron : 35,33% / 27,84%
- Jean-Luc Mélenchon : 30,09% / 21,95%
- Marine Le Pen : 5,54% / 23,15%


Also

RAG-time revisited. Feb 18, 2008. (RAG: Ralph, Al, George) (quasi-stochastic poetry)  https://inkpi.blogspot.com/2008/02/2152-rag-time-revisited.html

RAGtime revisited inside last #POTUS races: past ("pulsatile") trick, THEN treat, THEN ... (?)  Apr 1, 2016  https://flashontrack.blogspot.com/2016/04/s-usa-ragtime-revisited-inside-last.html

prospettiche meta- geometriche meta- fusioni, by Cedric. May 19, 2017.  https://flashontrack.blogspot.com/2017/05/n-soc-prospettiche-meta-geometriche.html

Aussi  (Wed April 13, 2022 11:05)

<< Electeurs de Jean-Luc Mélenchon : 43 % pour Emmanuel Macron, 28 % pour Marine Le Pen, 29 % abstention, vote blanc ou nul. >>

SONDAGE EXCLUSIF - Présidentielle : 43 % des électeurs de Jean-Luc Mélenchon prêts à voter pour Emmanuel Macron. Par Alexandre Rousset. Publié le 12 avr. 2022 à 14:07 Mis à jour le 13 avr. 2022 à 9:06


keywords: life, rag-time




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lunedì 11 aprile 2022

# gst: apropos of instabilities, viscoelastic liquid bridges can be destabilized by torsion.

<< Liquid bridges are formed when liquids are constrained between two (or more) surfaces via the capillary force. They appear in a wide range of contexts including biology, medicine, and engineering. In the context of biology, liquid bridges enable animals like geckos to adhere to vertical walls (..) >>

<< By experiment and simulation, (AA) report that viscoelastic liquid bridges made of constant viscosity elastic liquids, a.k.a. Boger fluids, can be effectively destabilized by torsion. Under torsion, the deformation of the liquid bridge depends on the competition between elastocapillarity and torsion-induced normal stress effects. When the elastocapillary effect dominates, the liquid bridge undergoes elastocapillary instability and thins into a cylindrical thread, whose length increases and whose radius decays exponentially over time. When the torsion-induced normal stress effect dominates, the liquid bridge deforms in a way similar to edge fracture, a flow instability characterized by the sudden indentation of the fluid's free surface when a viscoelastic fluid is sheared at above a critical deformation rate. The vertical component of the normal stress causes the upper and lower portions of the liquid bridge to approach each other, and the radial component of the normal stress results in the liquid bridge thinning more quickly than under elastocapillarity. Whether such quick thinning continues until the bridge breaks depends on both the liquid bridge configuration and the level of torsion applied. >>️

San To Chan, Stylianos Varchanis, et al. Torsional instability of constant viscosity elastic liquid bridges. Soft Matter, 2022,18, 1965-1977. doi: 10.1039/ D1SM01804C. Feb 7, 2022. 



Also

keyword 'instability' | 'instabilities' in FonT



keyword 'instabile' in Notes (quasi-stochastic poetry)


keyword 'torsione' in Notes (quasi-stochastic poetry)


keywords: instability, torsion, torsional instability, viscoelastic liquid, bridge







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sabato 9 aprile 2022

# phyto: weird, jazzy Nature, the 'transference of sexuality', 'some sexual consequences of being a plant'.

<< Plants have characteristic features that affect the expression of sexual function, notably the existence of a haploid organism in the life cycle, and in their development, which is modular, iterative and environmentally reactive. For instance, primary selection (the first filtering of the products of meiosis) is via gametes in diplontic animals, but via gametophyte organisms in plants. Intragametophytic selfing produces double haploid sporophytes which is in effect a form of clonal reproduction mediated by sexual mechanisms. In homosporous plants, the diploid sporophyte is sexless, sex being only expressed in the haploid gametophyte. However, in seed plants, the timing and location of gamete production is determined by the sporophyte, which therefore has a sexual role, and in dioecious plants has genetic sex, while the seed plant gametophyte has lost genetic sex. This evolutionary transition is one that E.J.H. Corner called ‘the transference of sexuality’. The iterative development characteristic of plants can lead to a wide variety of patterns in the distribution of sexual function, and in dioecious plants poor canalization of reproductive development can lead to intrasexual mating and the production of YY supermales or WW superfemales. Finally, plant modes of asexual reproduction (agamospermy/apogamy) are also distinctive by subverting gametophytic processes. >>

Quentin Cronk. Some sexual consequences of being a plant. Philos Trans R Soc Lond B Biol Sci. doi: 10.1098/ rstb.2021.0213. Mar 21, 2022. 


Also

keyword 'phyto' | 'plant' in FonT



keywords: evol, evolution, phyto, plant, sex, sexuality

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mercoledì 6 aprile 2022

# astro: going beyond a performance by Frank Zappa (or a speech by – for example – a political entity), two speeds of sound found on Mars

AA << find that atmospheric sounds extend measurements of pressure variations down to 1,000 times smaller scales than ever observed before, revealing a dissipative regime extending over 5 orders of magnitude in energy. Using point sources of sound (Ingenuity rotorcraft, laser-induced sparks), (AA) highlight two distinct values for the speed of sound that are ~10 m/s apart below and above 240 Hz, a unique characteristic of low-pressure CO2-dominated atmosphere. (They) also provide the acoustic attenuation with distance above 2 kHz, allowing to elucidate the large contribution of the CO2 vibrational relaxation in the audible range. >>

Maurice, S., Chide, B., Murdoch, N. et al. In situ recording of Mars soundscape. Nature. doi: 10.1038/ s41586-022-04679-0. Apr 1, 2022. 


<< All of these factors would make it difficult for two people to have a conversation only five meters (16 feet) apart >> Sylvestre Maurice.

Juliette Collen and Daniel Lawler. First audio recorded on Mars reveals two speeds of sound. Phys.org. Apr 1, 2022. 


NASA Perseverance Rover Captures 
Puff, Whir, Zap Sounds from Mars 


Also

Frank Zappa 


image from  


keywords: astro, mars, acoustics, sound, speed of sound, dissipative regimes, music, jazz, freejazz









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