Translate

Visualizzazione dei post in ordine di pertinenza per la query virus. Ordina per data Mostra tutti i post
Visualizzazione dei post in ordine di pertinenza per la query virus. Ordina per data Mostra tutti i post

giovedì 29 luglio 2021

# life: apropos of fuzzy cooperation, Ralph fuzzy mixture vs. world fuzzy dance ...

<< In 2013, the American virologist Ralph Baric approached Zhengli Shi at a meeting. Baric was a top expert in coronaviruses, with hundreds of papers to his credit, and Shi, along with her team at the Wuhan Institute of Virology, had been discovering them by the fistful in bat caves. In one sample of bat guano, Shi had detected the genome of a new virus, called SHC014, that was one of the two closest relatives to the original SARS virus, but her team had not been able to culture it in the lab. >>️

<< Baric had developed a way around that problem—a technique for “reverse genetics” in coronaviruses. Not only did it allow him to bring an actual virus to life from its genetic code, but he could mix and match parts of multiple viruses. He wanted to take the “spike” gene from SHC014 and move it into a genetic copy of the SARS virus he already had in his lab. The spike molecule is what lets a coronavirus open a cell and get inside it. The resulting chimera would demonstrate whether the spike of SHC014 would attach to human cells. >>️

<< Just as when you trade in part of a poker hand for fresh cards, there was no way of knowing whether the final chimeras would be stronger or weaker. >>

<< If you study a hundred different bat viruses, your luck may run out. >> Ralph Baric. 

<< In 2014, the NIH awarded a five-year, $3.75 million grant to EcoHealth Alliance to study the risk that more bat-borne coronaviruses would emerge in China, using the same kind of techniques Baric had pioneered. Some of that work was to be subcontracted to the Wuhan Institute of Virology. >>

<< Consider this hypothetical scenario, (..) An important gain-of-function experiment involving a virus with serious pandemic potential is performed in a well-regulated, world-class laboratory by experienced investigators, but the information from the experiment is then used by another scientist who does not have the same training and facilities and is not subject to the same regulations. In an unlikely but conceivable turn of events, what if that scientist becomes infected with the virus, which leads to an outbreak and ultimately triggers a pandemic >>  Anthony Fauci (director of the NIH’s National Institute of Allergy and Infectious Diseases) (2012).
<< Paul’s grilling of Fauci brought new scrutiny to the relationship between Ralph Baric’s lab at UNC and Zhengli Shi’s at WIV, with some narratives painting Baric as the Sith master of SARS and Shi as his ascendant apprentice. They did share resources—for example, Baric sent the transgenic mice with human lung receptors to Wuhan.  >>
<< During a hearing on May 11, 2021, Senator Rand Paul confronted Anthony Fauci over funding of bat-virus research by the National Institutes of Health. >>️

<< The NIH has still not fully explained its decision-making and did not reply to questions. Citing a pending investigation, it has declined to release copies of the grant that sent the Wuhan institute about $600,000 between 2014 and 2019. It has also revealed little about its new system for assessing gain-of-function risks, which is carried out by an anonymous review panel whose deliberations are not made public. >>️
Rowan Jacobsen. Inside the risky bat-virus engineering that links America to Wuhan. China emulated US techniques to construct novel coronaviruses in unsafe conditions. MIT TechRev. Jun 29, 2021. 


Also

<< " ... e Da-Li' si sparse pell' aere un fantasmatico ente supersintetico supercompresso ... >> in: ️2153 - cracker tendenziali (around a matter-sucking maelstrom). Notes. Apr 4, 2008. (quasi-stochastic poetry)


<< in attesa del beffardo tsunami. >> in: 1619 - onda di carambola. Notes. Nov 29, 2004. (quasi-stochastic poetry).

keyword 'virus' in Notes (quasi-stochastic poetry)


keyword 'virus' in FonT 


keyword 'caos' | 'caotico' in Notes (quasi-stochastic poetry)



FonT

no surprise, no amazement here, I know chickens behaviors. 

<< Ricordo che quando si era ragazzi, negli anni sessanta, ... >> in: 2157 - il pino di takata matsubara. Apr 1, 2011. Notes. 








domenica 13 marzo 2016

# s-epidemiol: climate change plus Zika, then a behavioral transition, hat burqa- like everywhere ...

<< “In  many ways  the  Zika  outbreak  is  worse  than the  Ebola  epidemic  of 2014-15,” said  Jeremy  Farrar, head of the Welcome  Trust.  “Most  virus  carriers  are  symptomlessIt  is  a  silent  infection  in  a  group  of highly  vulnerable  individuals  –  pregnant  women  –  that  is  associated  with  a  horrible  outcome  for  their babies.” There  is  no  prospect  of a  vaccine  for  Zika  at  present,  in  contrast  to  Ebolafor  which  several are  now under  trial“The  real problem is  that  trying  to  develop  a  vaccine  that  would  have  to  be  tested  on pregnant  women is  a  practical and  ethical nightmare,”  added  Mike  Turner,  head  of infection  and immuno-biology at the Welcome  Trust >>

Robin  McKie. Saturday 30 Jan 2016  20.10  GMT. Zika  virus  could  be  bigger  global  health  threat  than Ebolasay  health  experts.

http://www.theguardian.com/world/2016/jan/30/zika-virus-health-fears

<<
What we know

No vaccine exists to prevent Zika virus disease (Zika).

Prevent Zika by avoiding mosquito bites (see below).

Mosquitoes that spread Zika virus bite mostly during the daytime.

Mosquitoes that spread Zika virus also spread dengue and chikungunya viruses.
>>

Zika virus. Prevention. 13/03.2016

http://www.cdc.gov/zika/prevention/index.html

mercoledì 8 marzo 2023

# life: apropos of 1or2achoos (from Wuhan), here is a triptych on the subject.


Apropos of 1or2achoos from Wuhan, here is a triptych on the subject. 

( by Rhiannon Williams. The White House is split over covid’s origins. MIT - The Download. Feb 28, 2023. 


(1)
<< The White House said there is no consensus within the Biden administration over the origins of the Covid-19 virus, a day after the disclosure of an Energy Department assessment that the pandemic most likely originated with a leak from a Chinese lab. >>

Josh Chin, Lindsay Wise, Annie Linskey. White House Says No Consensus on Covid Origin. Comments follow Energy Department assessment that pandemic likely started with leak from Chinese lab. WSJ. Feb. 27, 2023. 

(2)
<< The U.S. Energy Department has concluded that the Covid pandemic most likely arose from a laboratory leak, according to a classified intelligence report recently provided to the White House and key members of Congress. The shift by the Energy Department, which previously was undecided on how the virus emerged, is noted in an update to a 2021 document by Director of National Intelligence Avril Haines’s office. >>

Michael R. Gordon, Warren P. Strobel. Lab Leak Most Likely Origin of Covid-19 Pandemic, Energy Department Now Says. U.S. agency’s revised assessment is based on new intelligence. WSJ. Feb. 26, 2023.

(3)
<< Shi Zhengli has spent years at the Wuhan Institute of Virology researching coronaviruses that live in bats. Her work has come under fire as the world tries to understand where covid-19 came from. >>

Jane Qiu. Meet the scientist at the center of the covid lab leak controversy.  MIT Tech Rev. Feb 9, 2022. 

Also

<< Qui l'approccio semplice, diretto, efficace che ho usato per la prevenzione ed eventuale gestione personale dell'entità coronavirus /  SARS-COV-2 (SARS: Severe Acute Respiratory Syndrome ) >>

(Here is the simple, direct, effective approach that I used for the prevention and possible personal management of the coronavirus entity)

# life: aproposito di '1or2achoos' (da Wuhan (?)) ... FonT. Jul 13, 2022. 

Also

keyword 'virus' in FonT

keyword 'virus' in Notes 
(quasi-stochastic poetry)

Keywords:  virus, flu, coronavirus, 2019-ncov, 2019ncov, SARS-CoV-2, sarscov2, covid-19, covid19, 1or2achoos, mask


mercoledì 24 marzo 2021

# life: a tiny pill against two unfavorable hypotheses on serial coronavirus pandemics - to avoid the socio-economic psycho-behavioral fallout caused by 1or2achoos (e.g. from Wuhan)

<< Pfizer Inc. said it has begun human safety testing of a new pill to treat the coronavirus that could be used at the first sign of illness. If it succeeds in trials, the pill could be prescribed early in an infection to block viral replication before patients get very sick. The drug binds to an enzyme called a protease (Pfizer’s oral protease inhibitor, code-named PF-07321332,) to keep the virus from replicating. >>

<< In lab tests, it worked against many coronaviruses, including the original SARS virus and MERS. Additionally, the coronavirus protease doesn’t mutate much, which means the therapy is likely to work equally well against numerous variant strains, >>
<< This is really a potential game changer, >>️  Mikael Dolsten️

Robert Langreth. Pfizer Begins Human Trials of New Pill to Treat Coronavirus
Mar 23, 2021 17:38 CET. 


Christie Aschwanden. Five reasons why COVID herd immunity is probably impossible. Nature 591, 520-522. doi: 10.1038/ d41586-021-00728-2. Mar 18, 2021. 


Angela L. Rasmussen, Saskia V. Popescu. SARS-CoV-2 transmission without symptoms.  Science, 2021; 371 (6535): 1206-1207 doi: 10.1126/ science.abf9569   


Also

keyword 'virus' in FonT


keyword 'virus' in Notes (quasi-stochastic poetry):



giovedì 12 marzo 2020

# gst: apropos of 'reprogrammed by a virus' (2), the case of 'virocells'

<< If it looks like a duck and quacks like a duck, so the adage goes, it must be a duck. But if the duck gets infected by a virus so that it no longer looks or quacks like one, is it still a duck? >>

Viruses reprogram cells into different virocells. DOE/Joint Genome Institute. 
 Feb 11, 2020.

https://m.phys.org/news/2020-02-viruses-reprogram-cells-virocells.html

<< Ocean viruses are abundant and infect 20–40% of surface microbes. Infected cells, termed virocells, are thus a predominant microbial state. Yet, virocells and their ecosystem impacts are understudied, thus precluding their incorporation into ecosystem models. >>

AA << investigated how unrelated bacterial viruses (phages) reprogram one host into contrasting virocells with different potential ecosystem footprints. >>

<< Ecologically, this work suggests that one cell, infected versus uninfected, can have immensely different metabolisms that affect the ecosystem differently. >>

Howard-Varona C, Lindback MM, et al. Phage-specific metabolic reprogramming of virocells. ISME J. doi: 10.1038/s41396-019-0580-z. Jan 2, 2020.

https://www.nature.com/articles/s41396-019-0580-z

Also

keyword 'virus' in FonT

https://flashontrack.blogspot.com/search?q=virus

keyword 'virus' in Notes (quasi- stochastic poetry)

https://inkpi.blogspot.com/search?q=virus


sabato 22 agosto 2020

# life: oops! IT entity (i.e. 1or2 'achoo!' from Wuhan) seems to be alive ... here a review of candidate drugs against SARS-CoV-2 and COVID-19.

<< Outbreak and pandemic of coronavirus SARS-CoV-2 in 2019/2020 will challenge global health for the future. Because a vaccine against the virus will not be available in the near future, we herein try to offer a pharmacological strategy to combat the virus. There exists a number of candidate drugs that may inhibit infection with and replication of SARS-CoV-2. >>

McKee DL, Sternberg A, et al. Candidate drugs against SARS-CoV-2 and COVID-19. Pharmacol Res. 2020;157:104859. doi: 10.1016/ j.phrs.2020.104859


Also

(this is a keyword list, copy & paste in Search Pubmed)

("antiviral drugs"[all] AND "SARS-CoV-2"  AND  "last 1 years"[PDat])


Also

keyword 'virus' in FonT


keyword 'virus' in Notes (quasi-stochastic poetry):





venerdì 10 dicembre 2021

# life; apropos of #1or2achoos from Wuhan ...

Messrs. A, B, C & D state - between the lines, undertrack, at least a year late -

Commissione DuPre (Dubbio e Precauzione ) live streaming 8/12/2021 


that the official anti covid19 apparatus it appears to be a big, very big mess (i.e. 'un grande pastrokkio') ...

probably Messrs. A, B, C & D could be accused of being thieves, sexual maniacs, they could block their career and make their spouses do twenty years of precariousness ...

their future pensioners' allowance could be taken away or reduced ... 

as well as more ... 

I suppose & anzicheforse ...

luckily for everyone, the 'bushman  variant' of sarscov-2 (Covid-19 B.1.1.529 Omicron) 

Republic of Botswana - new covid 19 variant detected in Botswana -  Presidential covid-19 task force.


could save in short-term, perhaps, the world from this big trouble (i.e.  'grande impiccio').

Here there are three simple questions: 

(a) Why in anticipation of the 'great tea trolley disaster' (after SARS appearance in Nov 2002, Guangdong, China; after MERS in Nov 2012, Gedda, Saudi Arabia) spray forms of antiviral drugs (e.g. remdesivir,  remdesivir like) have not been prepared?


(b) Why in the meantime, hitech reusable anti-viral anti-bacterial fabrics not been studied and tested?

(c) Does it seem serious to propose a vaccine - to treat every six/eight months eight billion people inside a window of 15/30 days - to confine (sic) a mutant virus (one mutation every week) that is transmitted by air? 

Also 

the unmentionable GTTD - Great Tea Trolley Disaster, by Bristow


keyword 'virus' | 'sars-cov-2' | 'sars' in FonT




keyword 'virus' in Notes 
(quasi-stochastic poetry):


keyword 'bosciman*' | 'nomad*' in Notes
(quasi-stochastic poetry)





keyword 'bushmen' | 'nomads' in FonT 



keywords: virus, coronavirus, sars, mers, sars-cov-2, covid-19, 2019ncov, bushman  variant, B.1.1.529, Omicron, 1or2achoos, mask


mercoledì 15 luglio 2020

# evol: iterative hacking mechanics; a large group of viruses can assemble human-virus codes to produce novel chimeric (UFO) proteins

<< Like a scene out of "Invasion of the Body Snatchers," a virus infects a host and converts it into a factory for making more copies of itself. Now researchers have shown that a large group of viruses, including the influenza viruses and other serious pathogens, steal genetic signals from their hosts to expand their own genomes. >>

AA << looked at a large group of viruses known as segmented negative-strand RNA viruses (sNSVs), which include widespread and serious pathogens of humans, domesticated animals and plants, including the influenza viruses and Lassa virus (..) by stealing genetic signals from their hosts, viruses can produce a wealth of previously undetected proteins. The researchers labeled them as UFO (Upstream Frankenstein Open reading frame) proteins, as they are encoded by stitching together the host and viral sequences. There was no knowledge of the existence of these kinds of proteins prior to this study. >>

Viruses can steal our genetic code to create new human-virus genes. The Mount Sinai Hospital. Jun 18, 2020.


Jessica Sook Yuin Ho, Matthew Angel, et al. Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection. Cell. Vol 181, Issue 7, P1502-1517.e23. doi: 10.1016/ j.cell.2020.05.035. June 25, 2020. 



giovedì 24 agosto 2017

# ecol: reprogrammed by a virus

AA << work demonstrates how a virus can amend host–viral dynamics by modulating acquisition of nutrients from the environment >>

AA << data show that a virus can acquire genes encoding nutrient transporters from a host genome and that expression of the viral gene can alter the nutrient uptake behavior of host cells >>

AA << results have implications for understanding how viruses manipulate the physiology and ecology of phytoplankton, influence marine nutrient cycles, and act as vectors for horizontal gene transfer >>

Adam Moniera, Aurelie Chambouvet, et al. Host-derived viral transporter protein for nitrogen uptake in infected marine phytoplankton. PNAS doi: 10.1073/pnas.1708097114

http://m.pnas.org/content/early/2017/08/17/1708097114

<< A virus which infects ocean plankton can reprogramme cells and change the way they absorb nutrients - potentially changing how carbon is stored in the ocean >>

Virus reprograms ocean plankton.
Aug 21, 2017

https://m.phys.org/news/2017-08-virus-reprograms-ocean-plankton.html

giovedì 14 aprile 2022

# life: a weird revisited from ethnomedicine inside an approach in epidemiology, the 'saliva healers' vs. 'herd immunity'.

(A) 
<< chiamati 'dottori della saliva' >>
A pain-suppressive effect. Notes (quasi-stochastic poetry). Nov 14, 2006.    


(B) 
Apropos of "herd immunity" ... FonT. Mar 16, 2020. 


(C) 
<< During 2020, most schools were never pro-actively closed to hinder virus spreading (with compulsory physical attendance required by law in Sweden and no option for distance or home learning)  >> 

<< Many elderly people were administered morphine instead of oxygen despite available supplies, effectively ending their lives. >>️

<< The Swedish Strategy was also influential abroad, and became an argument in other countries including, among others, the United States (US), United Kingdom (UK) and Australia, to loosen restrictions >>️ 

<< Supporters of the natural herd-immunity strategy promoted a widespread “controlled” spread in society, to obtain herd-immunity without vaccination >>️ 

<< Email conversations and statements from the State Epidemiologist and others show that they at least speculated on the use of children to acquire herd-immunity, while at the same time publicly claiming children played a negligible role in transmission and did not become ill >> 

<< During 2020, however, Sweden had ten times higher COVID-19 death rates compared with neighbouring Norway. >>️️
Nele Brusselaers, David Steadson, et al. Evaluation of science advice during the COVID-19 pandemic in Sweden. Humanit Soc Sci Commun 9, 91. doi: 10.1057/ s41599-022-01097-5. Mar 22, 2022.  


Also

keyword 'saliva' in Notes  (quasi-stochastic poetry)   


keyword 'saliva' in FonT   


keyword 'virus' | 'sars-cov-2' | 'sars' in FonT   




keyword 'virus' in Notes (quasi-stochastic poetry):


Also

(here a homemade mask with a pre  antiviral spray mixture)

A funky, immediate approach of the sneezing from Wuhan (a relative safe barrier - this device is NOT a filter). FonT. Mar 20, 2020. 


keywords: ethnomedicine, saliva, saliva healers, herd immunity, virus, coronavirus, sars, mers, 2019ncov, sarscov2, covid19, 1or2achoos 








martedì 28 aprile 2020

# gst: how a virus could cause context-dependent manipulation in host social behavior

<< Honey bees that guard hive entrances are twice as likely to allow in trespassers from other hives if the intruders are infected with the Israeli acute paralysis virus, a deadly pathogen of bees, >>

<< It seems that the virus is changing how the bees smell, and perhaps the infected bees also are behaving in a way that is meant to appease the guards by engaging more in trophallaxis (a process by which honey bees exchange regurgitated food and other liquids), >> Adam Dolezal

Diana Yates. Virus-infected honey bees more likely to gain entrance to healthy hives. University of Illinois at Urbana-Champaign. April 27, 2020.

https://phys.org/news/2020-04-virus-infected-honey-bees-gain-entrance.html

Amy C. Geffre, Tim Gernat, et al. Honey bee virus causes context-dependent changes in host social behavior. PNAS  doi: 10.1073/pnas.2002268117. Apr 27, 2020.

https://www.pnas.org/content/early/2020/04/21/2002268117

keyword 'trophallaxis' in Britannica

https://www.britannica.com/search?query=Trophallaxis

mercoledì 13 luglio 2022

# life: aproposito di '1or2achoos' (da Wuhan (?)) ...


a proposito di '1or2achoos' (da Wuhan (?)) ... cfr Weekly epidemiological update on COVID-19 - 6 July 2022. Edition 99. Emergency Situational Updates. https://www.who.int/publications/m/item/weekly-epidemiological-update-on-covid-19---6-july-2022   img   https://cdn.who.int/media/images/default-source/mca/mca-covid-19/coronavirus-2.tmb-768v.jpg?sfvrsn=4dba955c_12 

Qui l'approccio semplice, diretto, efficace che ho usato per la prevenzione ed eventuale gestione personale dell'entità coronavirus /  SARS-COV-2 (SARS: Severe Acute Respiratory Syndrome ) 

In data 20 Marzo 2020 ho pubblicato sul mio blog FonT - e, giusto per intendersi, ho contemporaneamente inviato il testo a una mia mail criptata - un approccio nell'ipotesi di disattivare / spegnere il coronavirus (sars-cov-2) che causa covid-19;   

Qui il link   ('you can get more security by spraying...)'   https://flashontrack.blogspot.com/2020/03/life-funky-immediate-approach-of.html

L'approccio pubblicato consisteva nell'uso di una soluzione di alcool (uso alimentare, 96%), perossido di idrogeno (3%) e acqua da nebulizzare con un generico dosatore spray tascabile (usato per nebulizzare profumi); 

La stechiometria di due dei tre componenti (alcool e perossido di idrogeno) era indicata sul sito del WHO (e consigliata per disinfettare superfici);

Qui il link attuale del doc 
12 WHO-recommended handrub formulations (2009) - Formulation I      
https://www.ncbi.nlm.nih.gov/books/NBK144054  che a quel tempo era presente, e attualmente assente, sul sito WHO al link 
e scaricabile nella forma di doc.pdf

Modificai la soluzione con la sostituzione di glicerolo con acqua per consentire la nebulizzazione del prodotto; 

Da allora ho sempre usato la miscela spray per disinfettare mani e mascherine di cotone (doppia mascherina, di cotone, riusabile, in posizione esterna e quando disponibile ffp2 in posizione interna); 

Tuttavia ho usato la stessa miscela per trattare i tre 'flu' (ipoteticamente covid-19) che ho contratto nei tre anni 2020, 2021 e 2022.  

In particolare, tutte le volte che ho avuto necessità di soffiare il naso (per secrezione mucosa, causa rinorrea) ho successivamente trattato entrambi naso e gola con la miscela spray; direttamente sulla mucosa orale e indirettamente nella mucosa nasale inspirando la soluzione preventivamente nebulizzata sul dorso della mano;

Nei primi due casi (2020 e 2021) ho spento il 'flu' in mezza giornata (in entrambe le situazioni non ero vaccinato); nel terzo caso ho spento il 'flu' in 2 giorni scarsi di trattamento (ero già stato vaccinato con le 2+1 dosi perchè obbligatorie in Italia specialmente per chi era iscritto all'Ordine dei Biologi e comunque per chi aveva raggiunto l'età di 50+ anni  
( OMS - Piano vaccini anti Covid-19

I flu precedenti al 2020 (circa 60 flu nell'arco di 70 anni di età, a ciclicità annuale) mi avevano sempre impegnato in circa tre giorni di pre- crisi, tre giorni di crisi a letto e tre giorni di post- crisi (convalescenza) per un totale di mai meno di quattro-cinque giorni di parziale compromissione dell'autonomia; 

Nelle mie tre individuali esperienze, confrontate con tutte le pregresse, l'immunità sembra essere stata quasi immediata, senza alcuna compromissione dell'autonomia.

Se (beninteso, se e solo se) le future risposte individuali del mio sistema immunitario alle future probabili ondate epidemiche da flu opp sars saranno equivalenti alle tre citate sopra, per quello che mi riguarda questa problematica si è chiusa a far data dal 20 marzo 2020, indipendentemente dalle future disponibilità di vaccini anti-flu anti-sars. 

Qui l'ipotetico meccanismo di azione.

I coronavirus (come i virus flu a causa di orthomyxoviridae) si duplicano nelle mucose orale e nasale; il capside virale ( e.g. Chung-ke Chang et al. Antiviral Res. 2014 Mar. https://pubmed.ncbi.nlm.nih.gov/24418573/ ) in presenza di alcool probabilmente si apre per denaturazione proteica e questo consente a un sistema immunitario fisiologicamente attivo di leggere sia il capside (che dovrebbe comunque conservare la struttura primaria) sia parti della sua metameccanica molecolare interna; 

Anche

keyword 'virus' | 'sars-cov-2' | 'sars' in FonT: 




keyword 'virus' in Notes 
(quasi-stochastic poetry):


Keywords: virus, flu, coronavirus,  sarscov2, covid19, 1or2achoos, mask

PS: certo è che i colleghi biomedici (qualunque cosa si intenda per  'colleghi' ), con l'epifanie SARS (Nov 2002, Guangdong, China; MERS,  Nov 2012, Gedda, Saudi Arabia, SARS-COV-2, 2019-2020, Wuhan, China) non sembra abbiano mostrato il consueto brillamento delle proprie loro medesime - senz'alcun dubbio elevatissime - potenzialità.  Per modo di dire ed anzicheforse ... Forse, talvolta, si tende a sottovalutare la lezione del Maestro, indimenticato, indimenticabile Jelly Roll:  "Amico, qualunque cosa suonerai ..."   https://flashontrack.blogspot.com/search?q=jelly+roll


sabato 17 aprile 2021

# life: apropos of '1or2achoos' (from Wuhan), 'Shame on us', by Jay.

<< The year 2003 was an ominous one for emerging infectious diseases. A pair of deadly influenza strains had leapt from birds to humans in Hong Kong and the Netherlands. And a new coronavirus was spreading around the world causing a mysterious illness that became known as severe acute respiratory syndrome, or SARS. Many experts feared they were watching the start of a global pandemic. Fortunately, the worst-case scenario never materialized. But it was a close-enough call for Robert Webster, a leading authority on avian influenza, to start urging scientists and policymakers to prepare for the next outbreak. One of his top recommendations: develop and stockpile drugs that target a wide range of viral pathogens. Drug researchers did not heed his call. After the SARS threat subsided, interest evaporated — and the world paid the price. “The scientific community really should have developed universal antivirals against SARS,” says Webster, now an emeritus member of St Jude Children’s Research Hospital in Memphis, Tennessee. “Then we would have had something in the stockpile for the emergence of COVID,” which is a caused by SARS-CoV-2, a close relative of the virus responsible for SARS. Another warning shot came in 2012, when Middle East respiratory syndrome (MERS) — caused by another relative of SARS-CoV-2 — started spreading through a handful of countries. Still, the drug shelves remained largely bare — a fact that Jay Bradner, president of the Novartis Institutes for BioMedical Research in Cambridge, Massachusetts, regards as “regrettable”. >>️

<< Shame on us, (..) We can be better prepared. >> Jay Bradner.️

<< We need an arsenal, >> Kara Carter.

<< It’s hard to convince a company to make a drug against something that doesn’t exist. >>️  Timothy Sheahan.

<< There’s a lot of work that needs to be done, (..) We don’t want to have another year like 2020, (..) and we don’t have to, if we do the work in advance. >> Nat Moorman.️
Elie Dolgin. The race for antiviral drugs to beat COVID — and the next pandemic. Despite dire warnings, a stockpile of ready compounds to fight viral pandemics was sorely lacking. Can drugmakers finally do the right thing? Nature 592, 340-343. doi: 10.1038/ d41586-021-00958-4. Apr 14, 2021. 


Also

keyword 'virus' | 'sars-cov-2' in FonT



keyword 'virus' in Notes (quasi-stochastic poetry):


apropos of "herd immunity" ... , FonT,  Mar 16, 2020.





martedì 27 luglio 2021

# life: they ( NIH, Ralph Baric’s Univ.of North Carolina lab, Wuhan Instit.of Virology ) never created a supervirus, anzicheforse ...

<< 
In May, the coronavirus researcher Ralph Baric found himself at the center of the debate over gain-of-function research ( https://www.technologyreview.com/2021/06/29/1027290/gain-of-function-risky-bat-virus-engineering-links-america-to-wuhan ), in which scientists engineer new properties into existing viruses. And during a congressional hearing, Senator Rand Paul implied that the National Institutes of Health had been funding such research at both the Wuhan Institute of Virology and Baric’s University of North Carolina lab, and that the two labs had been collaborating to make “superviruses”. Baric released a statement clarifying the research in question did not qualify as gain-of-function, and none of the SARS-like coronaviruses he’d used in the experiments were closely related to SARS-CoV-2, yet that did little to quell questions about the role his research may have played in furthering scientists’ ability to modify coronaviruses in potentially dangerous ways. Baric believes such research is essential to the development of vaccines and other countermeasures against emerging viruses, a project he has been engaged in for more than 20 years. His research laid the groundwork for the first approved anti-covid drug and helped speed the development of the mRNA vaccines that have proved so pivotal. 
MIT Technology Review recently asked Baric to explain what constitutes a gain-of-function experiment, why such research exists, and whether it could have played any role in the pandemic. Read the full interview. ( https://www.technologyreview.com/2021/07/26/1030043/gain-of-function-research-coronavirus-ralph-baric-vaccines )
>>️

Rowan Jacobsen. Why researchers need to tinker with viruses. The Download from MIT Technology Review newsletters@technologyreview.com  
The Download from MIT (mail). Jun 26, 2021 14:12

Also

<< ... e Da-Li' si sparse pell' aere un fantasmatico ente supersintetico supercompresso ... >> in: ️2153 - cracker tendenziali (around a matter-sucking maelstrom). Notes. Apr 04, 2008. (quasi-stochastic poetry)


keyword 'virus' in Notes (quasi-stochastic poetry)


keyword 'virus' in FonT 




giovedì 29 ottobre 2020

# life: aprops of 1or2 achoo! from Wuhan (SARS-CoV-2), a mask build of 'nanofibers randomly land on a collector to create a sort of non-woven mesh'

<< Recently, students from BYU’s College of Engineering teamed up with Nanos Foundation to develop a nanofiber membrane that can be sandwiched between the cloth pieces in a homemade mask. While today’s typical cloth mask might block fewer than 50% of virus particles, the membrane — which can be made using simple, inexpensive materials — will be able to block 90 to 99% of particles, increasing effectiveness while preserving breathability. The membranes are made through a process called “electrospinning,” which involves dissolving a polymer plastic in a solution and then using an electrical current to move a droplet of the polymer downward through a needle. As the droplet accelerates, it stretches into a very small fiber that retains a static charge. >>

<< Those nanofibers randomly land on a collector to create a sort of non-woven mesh, >> Katie Varela.

Christie Allen. With innovative nanofiber membranes, cloth masks’  efficacy goes up to 99%. Oct 21, 2020.



Also

keyword 'virus' in FonT


keyword 'virus' in Notes (quasi-stochastic poetry):




lunedì 30 agosto 2021

# gst: apropos of 1or2achoos (e.g. from Wuhan), the dynamics of turbulence in a fluid puff

<< Turbulence is everywhere -- in the movement of the wind, the ocean waves and even magnetic fields in space. It can also be seen in more transient phenomena, like smoke billowing from a chimney, or a cough. (..) Understanding this latter type of turbulence -- called puff turbulence -- is important not only for the advancement of fundamental science, but also for practical health and environmental measures, >>️

<< The very nature of turbulence is chaotic, so it's hard to predict, (..) Puff turbulence, which occurs when the ejection of a gas or liquid into the environment is disrupted, rather than continuous, has more complicated characteristics, so it's even more challenging to study. But it's of vital importance -- especially right now for understanding airborne transmission of viruses like SARS-CoV-2. >>️ Marco Edoardo Rosti. 

<< The new model, (..) includes how minute fluctuations within the puff behave, and how both large-scale and small-scale dynamics are impacted by changes in temperature and humidity. (..) at cooler temperatures (15°C or lower), (AA) model deviated from the classical model for turbulence. >>️

<< In the classical model, turbulence reigns supreme -- determining how all the little swirls and eddies within the flow behave. But once temperatures dipped, buoyancy started to have a greater impact. >>

<< The effect of buoyancy was initially very unexpected. It's a completely new addition to the theory of turbulent puffs,>> Marco Edoardo Rosti. ️

Secrets of COVID-19 transmission revealed in turbulent puffs. Okinawa Institute of Science and Technology (OIST). Aug 26, 2021. 


Andrea Mazzino, Marco Edoardo Rosti. Unraveling the Secrets of Turbulence in a Fluid Puff. Phys. Rev. Lett. 127, 094501. Aug 25, 2021. 


Also

keyword 'drop' | 'droplet' in FonT:



keyword 'turbulence' in FonT:


keyword 'turbolento' | 'turbolenza' in Notes (quasi-stochastic poetry): 



keyword 'virus' | 'sars-cov-2' | 'sars' in FonT




keyword 'virus' in Notes (quasi-stochastic poetry):



lunedì 7 febbraio 2022

# life; Hollywood (movies) revisited, you must be aware of the fact that Alien Entities will share our planet with us and, marginally, ...


Hollywood (movies) revisited, you must be aware of the fact that Alien Entities will share our planet with us and, marginally, will modify our neurobiology with physiological 'magic strings' virus-injected (*) to 'gently' subdue us.  Are you ready for all this, anzicheforse?

(*) virus-injected approach, motivated by the fact that Terrestrials use NOT to attack retroviruses with 'pastroky' vaccines ...

Also

<< David (Leonard David) said that extraterrestrials, however, could be aware of us and be deliberately ignoring our planet, which would represent an equally devastating blow to the human sense of self-importance. >>
<< We could be the dolts of the universe. >> Leonard David. 
 UFOs ‘Something’s coming’: is America finally ready to take UFOs seriously? Adam Gabbatt in New York
@adamgabbatt Sat 5 Feb 2022 08.00 GMT 


Also


keyword 'oops' in FonT


keyword 'magic string' in FonT


Also

Dr. J. Allen Hynek (Astronomer, the scientific consultant of the U.S. Air Force Project Sign (1948), Project Grudge (1949), Blue Book (1952–1969).


PS:  io non sono mai stato testimone di alieni o di manifestazioni di entità aliene. Tuttavia, forse (qui sottolineo forse), potrei averne frequentata una per decenni. Mia madre era per me una incognita; beveva l'essenziale, non fumava, non dormiva, mangiava poco, non si ammalava, era sempre in energico movimento. Passati i novanta anni di età - grondante di sudore, dopo avere trascorso, giusto per passare il tempo, un paio di ore a stirare nel mezzogiorno della calura agostana riminese - qualche volta l'ho sentita pronunciare la frase: "andrò a coricarmi perchè mi sento un po' stanca". Quando lei entrava in una stanza io immaginavo che virus e batteri sarebbero fuggiti terrorizzati per cercare di evitare quello che di lì a poco sarebbe potuto succedere. Lei era impermeabile a qualsivoglia ideologia o argomentazione che non si traducesse in immediata modalità operativa. Quale (apparente) paradosso, per lei era anche normale individuare e ribaltare immediatamente i punti chiave in merito a qualsiasi argomento. Anche se non lo dava a vedere, era una persona sostanzialmente avversa a qualsivoglia autorità imposta. Ricordo bene che le uniche tesi che non aggrediva erano quelle che trattavano la musica blues, il jazz, il rock - forse perchè intuiva che tali approcci fossero per sè stessi fondamentalmente auto-ribaltanti - e la chimica che, anche quando poteva contenere aspetti meramente speculativi, fantasmatici, lei avrebbe potuto comunque scorgere qualche indispensabile componente operativa osservazionale- sperimentale. 

Per questa sua unicità, dall'età di dieci anni fino ai quindici, ho avuto il sospetto che lei potesse essere il prodotto di qualche ignoto esperimento alieno. 

A distanza di decenni penso che mia madre, sebbene da bambina le avessero imposto di conseguire la sola istruzione elementare - come peraltro molte della sua generazione, sarebbe stata (terrestre o aliena) un valido 'naturale' co-addestratore nel team di una scuola Shaolin.

keywords: UFO, UFOs, UAP, EBE ,
AATIP, UAPTF ,OVNI , virus,  magic string, aliens, esobio, exobiology



venerdì 20 marzo 2020

# life: a funky, immediate approach of the sneezing from Wuhan (a relative safe barrier - this device is NOT a filter)

if (of course, if and only if) the problem is to save Western civilization from autocatalytic noise (and subsequent psychic, behavioral, political, economical, cultural catapulting collapse) caused by 1,2 sneezing of Wuhan, here a funky, immediate approach;

you have to get it: 

(1) thiny film (e.g. one piece of a thin film roll, made by polyethylene, used to wrap food);

(2) pocket cotton handkerchief  (like the ones used by cowboys, like those popping out of the pocket of the jackets that italian Prime Minister wears, perhaps wider);

(3) scotch tape (transparent adhesive tape);

below the assembly (1-3 minutes to compose it, two or 'n' times a day); 

This device is relatively safe even if your interlocutor spits in your mouth (in that  case, to protect the eyes you remember that you also need protective glasses and any earplugs, disposable gloves ...);

you can get more security by spraying - on the outside of the handkerchief - a mixture of alcohol, hydrogen peroxide (H2O2) and distilled water (the composition indicated by the WHO,  without glycerol);  cfr Guide to Local Production:  WHO-recommended Handrub Formulations  (reagents for formulation 1) Revised April 2010  

https://www.who.int/infection-prevention/tools/hand-hygiene/handrub-formulations/en

doc.pdf
https://www.who.int/gpsc/5may/Guide_to_Local_Production.pdf

With this device you can travel around the city, on buses, on trains, ... in relative safety, yours and your neighbors; 

instead of film roll for food you could use a waterproofing spray but the cost is high and the chemical one is probably toxic for human

Also

keyword 'virus' in FonT

https://flashontrack.blogspot.com/search?q=virus

keyword 'virus' in Notes (quasi- stochastic poetry)

https://inkpi.blogspot.com/search?q=virus

keyword 'snake' in FonT

https://flashontrack.blogspot.com/search?q=snake

keyword 'bat' in FonT

https://flashontrack.blogspot.com/search?q=bat

sabato 29 febbraio 2020

# life: Black Death way revisited, the hypothesis, by Parag.

<< Good afternoon to everyone online and in the room. (..) Since yesterday, Denmark, Estonia, Lithuania, Netherlands and Nigeria have all reported their first cases. All these cases have links to Italy. 24 cases have been exported from Italy to 14 countries, and 97 cases have been exported from Iran to 11 countries. >>  

Tedros Adhanom Ghebreyesus.

WHO Director-General's opening remarks at the media briefing on COVID-19. WHO. Feb 28, 2020.

https://www.who.int/dg/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19---28-february-2020

<< A striking overlap exists between the path of today's viral spread and the path of the Black Death in the 1300s. >>

<< It is, of course, far too soon to make such dire predictions about Covid-19. But a striking overlap exists between the path of today's viral spread and the path that emerged in the 1300s. >>

<< The 14th-century plague is said to have originated in northwestern China, with bacteria contracted from marmots. Hebei Province bore the brunt of China’s plague fatalities, with 5 million of its residents perishing in the 1330s. Making its way westward via Silk Road merchants and caravans, the plague took several years to reach Persia, where it killed the Khan overlord Abu Said as well as half the population. In 1347, it entered Europe via Italy’s port of Genoa. >>

<< Now compare that to what we’re seeing today with Covid-19. This time around, the source of illness may have been pangolins or bats instead of marmots. It started in Wuhan, which just happens to be Hebei's capital. The coronavirus reached Iran in a couple of weeks, and so far has infected hundreds of people, even the country’s deputy health minister. Next to Iran, the next worst outbreak is in Italy, with more than 300 cases and rising quickly- and likely spreading through Europe exactly as the plague did centuries ago. >>

<< It is, perhaps no coincidence that, in the past two decades, China has been the origin of SARS, the swine flu, and now the Covid-19 coronavirus. Nor should we be surprised that Iran and Italy have emerged, once more, as waypoints for pandemic spread. What do Iran and Italy have in common today? They are two major anchors of China’s Belt and Road Initiative- also known as the 21st century’s new Silk Roads. >>

Parag Khanna. IDEAS. Covid-19 Is Traveling Along the New Silk Road. Wired. Feb 28, 2020.

https://www.wired.com/story/covid-19-is-traveling-along-the-new-silk-road/

Also

keyword 'virus' by FonT

https://flashontrack.blogspot.com/search?q=virus

keyword 'virus' by Notes

https://inkpi.blogspot.com/search?q=virus


martedì 31 marzo 2020

# life: to save Western lifestyle from a catapulting collapse (caused by one or two Wuhan "achoo") use a techno mask (e.g. "cowboy" or "burqa" techno masks)

<< WHEN YOU LOOK at photos of Americans during the 1918 influenza pandemic, one feature stands out above all else: masks.  (..)  Newspapers published instructions for sewing masks at home. >>

<< After the 1918 pandemic, the prophylactic use of masks among the general public largely fell out of favor in America and much of the West. The US Centers for Disease Control and Prevention has almost never advised healthy people to wear masks in public to prevent influenza or other respiratory diseases. In the past few months, with medical supplies dangerously diminished, the CDC, US surgeon general Jerome Adams, and the World Health Organization have urged people not to buy masks, paradoxically claiming that masks are both essential for the safety of health care workers and incapable of protecting the public from Covid-19. >>

<< Recently, some experts have disputed this contradictory advice. They propose that widespread use of masks is one of the many reasons why China, Japan, South Korea, and Taiwan have controlled outbreaks of coronavirus much more effectively than the US and Europe. "Of course masks work," sociologist Zeynep Tufekci wrote in a New York Times editorial. "Their use has always been advised as part of the standard response to being around infected people." Public health expert Shan Soe-Lin and epidemiologist Robert Hecht made a similar argument in the Boston Globe (..) Last week, George Gao, director-general of the Chinese Center for Disease Control and Prevention, said that America and Europe are making a "big mistake" by not telling the public to wear masks during the ongoing pandemic. >>

<< N95s (N95 mask) are so-named because they filter out 95 percent of particles with a diameter of 0.3 microns, (..) Particles 0.3 microns wide are just the right size to ride a stream of air through a filter’s fibrous maze, but it is still possible to thwart them with enough twists and turns.>>

<< the bacterium that causes anthrax is 0.8 microns wide and 1.4 microns long, whereas influenza viruses and coronaviruses are usually between 0.08 and 0.12 microns. But microbes expelled from someone’s respiratory tract are rarely naked: the droplets they travel in range in size from 0.6 to more than 1,000 microns. >>

<< Although surgical masks are not tightly sealed like N95s, the filters they contain are still a major impediment to microbes. The CDC and other health agencies often say that surgical masks catch only spurts of bodily fluids and very large respiratory droplets, and that they cannot filter tiny infectious particles. But this is simply not true. >>

<< Because so many trials find only a marginal benefit or none at all, some health agencies have decided against recommending masks to the general public. But the inconsistency of randomized trials does not negate the robust physical evidence that masks block respiratory droplets and microbes.  >>

<< "To be honest, it’s common sense," says Tang (virologist Julian Tang). "If you put something in front of your face, it’s going to help more than not." If enough people wear masks at least somewhat correctly at least some of the time, the overall benefits could be dramatic. A 2011 review of high-quality studies found that among all physical interventions used against respiratory viruses-including handwashing, gloves, and social distancing-masks performed best, although a combination of strategies was still optimal. >>

It's Time to Face Facts, America: Masks Work. Official advice has been confusing, but the science isn't hard to grok. Everyone should cover up. Wired. Ideas. March 30, 2020.

https://www.wired.com/story/its-time-to-face-facts-america-masks-work/

Also 

a funky, immediate approach of the sneezing from Wuhan (a relative safe barrier - this device is NOT a filter) FonT.  Mar 20, 2020

https://flashontrack.blogspot.com/2020/03/life-funky-immediate-approach-of.html

Also

climate change plus Zika, then a behavioral transition, hat burqa- like everywhere ... FonT.  Mar13, 2016.

https://flashontrack.blogspot.com/2016/03/s-epidemiol-climate-change-plus-zika.html

Also

keyword 'virus' in FonT

https://flashontrack.blogspot.com/search?q=virus

keyword 'virus' in Notes (quasi- stochastic poetry)

https://inkpi.blogspot.com/search?q=virus

keyword 'snake' in FonT

https://flashontrack.blogspot.com/search?q=snake

keyword 'bat' in FonT

https://flashontrack.blogspot.com/search?q=bat