# life: apropos of saliva healers, herd immunity revisited and now hypothetically approachable even within NIH

<< President-elect Donald Trump is tapping Dr. Jay Bhattacharya, a Stanford University health researcher, to be the next director of the National Institutes of Health (NIH). >>

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<< Bhattacharya was one of three authors of the document (#1). The declaration called for speeding herd immunity by allowing people at low risk to get infected while protecting those most vulnerable, like the elderly. >>

Rob Stein. Trump turns to critic of COVID mandates to run NIH. npr.org. 

Nov 26, 2024. 

https://www.npr.org/sections/shots-health-news/2024/11/26/nx-s1-5195168/nih-bhattacharya-trump-election-2024

<< The most compassionate approach that balances the risks and benefits of reaching herd immunity, is to allow those who are at minimal risk of death to live their lives normally to build up immunity to the virus through natural infection, while better protecting those who are at highest risk. We call this Focused Protection. >>

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(#1) - Martin Kulldorff, Sunetra Gupta, Jay Bhattacharya. Great Barrington Declaration. Oct 4, 2020. https://gbdeclaration.org/

FonT

From my point of view 'herd immunity'  can be engineered if and only if, even in the case of sars-covid-19 or flu, simultaneous protection is used with an effective, easy available, antiviral drug.

In this regard, a non-compassionate but logical easy approach could be the indirect inhalation of alcohol ~70% already at the first signs of rhinorrhea, as follows:

(-) start self-treatment (spray plus cotton mask):

Mar 20, 2020  https://flashontrack.blogspot.com/2020/03/life-funky-immediate-approach-of.html  

(-) outcomes

Jul 13, 2022  https://flashontrack.blogspot.com/2022/07/life-aproposito-di-1or2achoos-da-wuhan.html  

Oct 4, 2023 https://flashontrack.blogspot.com/2023/10/life-proposito-di-1or2achoos-da-wuhan.html  

Ultimately, here it could hypothesize a case of historic, singular checkmate of 'one against all'. Anzicheforse?

Also: drop, saliva, sars* covid* (aka 1or2achoos), virus, ethno, Mr. Donald, POTUS, tit-for-tat, game, in https://www.inkgmr.net/kwrds.html 

Keywords: life, drop, saliva, saliva healers, herd immunity, sars, mers, 2019ncov, sarscov2, covid19, coronavirus, 1or2achoos, virus, ethno, ethnomedicine, Donald, POTUS, tit-for-tat, game

PS: I couldn't say why, but in certain contexts, the incipit of an answer that the physicist Enrico Fermi https://it.m.wikipedia.org/wiki/Enrico_Fermi  gave to a journalist always comes back to my mind: 'the physics that is done in our laboratory ...' . 

An example of exceptional, clear, even poetic analysis and synthesis skills (in only 8 words).

# game: Parrondo's paradox reveals counterintuitive wins in biology and decision making in society.

<< 

• Parrondo's paradox illustrates how combining two losing strategies can result in a winning outcome.

• Its applications extend across various disciplines, particularly in understanding ecosystems at different scales.

• The paradox is explored in multiple fields, highlighting adaptability as a key factor in evolutionary survival.

• Future directions are outlined, emphasizing the potential to enhance our understanding of the natural world and society.

 >>️

Tao Wen, Kang Hao Cheong. Parrondo's paradox reveals counterintuitive wins in biology and decision making in society. Physics of Life Reviews. 51, 33-59. Dec 19, 2024. 

https://www.sciencedirect.com/science/article/abs/pii/S1571064524000940 

Also: Parrondo, game, tit-for-tat, in https://www.inkgmr.net/kwrds.html 

Also: 'Parrondo paradox', in Pubmed  https://pubmed.ncbi.nlm.nih.gov/?term=parrondo+paradox&sort=date&size=50

Keywords: gst, Parrondo, game, tit-for-tat

FonT: as mentioned elsewhere in this blog, from my point of view, if well modulated, the two paired strategies "Stochastic Tit-For-Tat" and "Parrondo" are deadly, regardless of the aims of the objectives (cooperative purposes, parasitism, resurfacing of hypothetical clusters of failed entities, ... )

# game: aperiodic Parrondo (behavior based on the binary Fibonacci, Thue–Morse and Rudin–Shapiro sequences); persistence and heterogeneity effects.

AA << study the effectiveness of employing archetypal aperiodic sequencing -- namely Fibonacci, Thue-Morse, and Rudin-Saphiro -- on the Parrondian effect. From a capital gain perspective, (their) results show that these series do yield a Parrondo's Paradox with the Thue-Morse based strategy outperforming not only the other two aperiodic strategies but benchmark Parrondian games with random and periodical (AABBAABB…) switching as well. The least performing of the three aperiodic strategies is the Rudin-Shapiro. >>

AA << analyze the cross-correlation between the capital generated by the switching protocols and that of the isolated losing games. This analysis reveals that a pronounced anti-correlation (below -0.95) with both isolated games is typically required to achieve a robust manifestation of Parrondo's effect. >>

About << the influence of the sequencing on the capital using the lacunarity and persistence measures (AA) observe that the switching protocols tend to become less performing in terms of the capital as one increases the persistence and thus approaches the features of an isolated losing game. >>

Respect to << lacunarity, a property related to heterogeneity, (AA) notice that for small persistence the performance increases with the lacunarity with a maximum (..). In respect of this, (AA) work shows that  the optimisation of a switching protocol is strongly dependent on a fine tune between persistence and heterogeneity. >>

Marcelo A. Pires, Erveton P. Pinto, et al. Parrondo's effects with aperiodic protocols. arXiv: 2410.02987v1 [physics.soc-ph]. Oct 3, 2024.

https://arxiv.org/abs/2410.02987

Also: Parrondo, tit-for-tat, game, behav, network, in https://www.inkgmr.net/kwrds.html 

Keywords: Parrondo, tit-for-tat, game, behavior, behaviour, network

# game: apropos of Parrondo's paradox, winning with losses driven by reputation and reciprocity

AA << investigate two such social behaviors, reputation and reciprocity, and their role in explaining Darwin’s survival of the fittest, examining how these fundamental principles govern individual interactions and shape broader social dynamics. >>

<< Current theories hint at two main facets of social interaction, reputation and reciprocity, as potential drivers behind this cooperative evolution. Reputation revolves around building and sustaining trust, social worth, and overall community standing. Conversely, reciprocity governs the mutual exchange of actions or benefits, influencing our choices. >>

<< One intriguing concept explored in this domain is Parrondo’s paradox: combining or switching between two losing strategies might surprisingly achieve a winning outcome. The role of Parrondo’s paradox in complex systems has sparked key research into chaotic many-body, quantum, and algorithmic network applications, where combining elements yields opposing beneficial results. Similarly, social physicists aim to uncover hidden mechanisms that govern societal phenomena by integrating the paradox’s counterintuitive principles. >>️

<< The game-theoretic Parrondo’s paradox emerges through multiple iterations of these interactions (..) A naive observation might conclude that in either scheme the chance of individuals losing to the environment is higher than gaining from the environment. For the reputation scheme, one is rewarded with a singular capital from the environment but is punished with two. Similarly, the reciprocity scheme only allows for the redistribution of capital or loss of capital. In reality, diverse schemes can be adopted by different individuals. Thus, (AA) suggest two forms of switching: (1) stochastic switching, where the individual randomly selects one of two schemes to employ with equal probability, and (2) rule-based switching, where the individual only selects the reputation scheme if it passes the reputation threshold ρ; otherwise, it employs the reciprocity scheme. >>

AA << also performed simulations on other network topologies (..) Parrondo’s paradox is strongly observed in small-world networks, weakly in the Erdős-Rényi network, and absent in scale-free networks. >>

To conclude, some of these observations << underscore the profound capability of rule-based switching mechanisms inherent in Parrondo’s paradox to emulate and forecast key aspects of real-world social phenomena. Such insights are invaluable for developing sophisticated models and strategies in various fields, ranging from social sciences to policy making, where accurate predictions of social behavior and dynamics are crucial. >>

Joel Weijia Lai, Kang Hao Cheong. Winning with Losses: The Surprising Success of Negative Strategies in Social Interaction Behavior. Phys. Rev. Lett. 133, 167401. Oct 16, 2024. 

https://journals.aps.org/prl/abstract/10.1103/PhysRevLett.133.167401

Also: Parrondo, tit-for-tat, game, behav, network, in https://www.inkgmr.net/kwrds.html 

Keywords: Parrondo, tit-for-tat, game, behavior, behaviour, network

# gst: transitions by coupled instabilities

AA << present an experimental study of quasiperiodic transitions between a highly ordered square-lattice pattern and a disordered, defect-riddled state, in a circular Faraday system. (They)  show that the transition is driven initially by a long-wave amplitude modulation instability, which excites the oscillatory transition phase instability, leading to the formation of dislocations in the Faraday lattice. The appearance of dislocations dampens amplitude modulations, which prevents further defects from being created and allows the system to relax back to its ordered state. The process then repeats itself in a quasiperiodic manner. >>

Valeri Frumkin, Shreyas Gokhale. Coupled instabilities drive quasiperiodic order-disorder transitions in Faraday waves. Phys. Rev. E 108, L012601. July 17, 2023. 

https://journals.aps.org/pre/abstract/10.1103/PhysRevE.108.L012601

Also: parrondo, tit-for-tat, game, transition, chaos, in https://www.inkgmr.net/kwrds.html

Keywords: parrondo, tit-for-tat, game,  transition, chaos

# game: apropos of perpetual hack, to bypass 'lizard' brains with a Tit-for-Tat approach

<< In (..) lizard brain, (..) "cheating" was really just "retaliation." >>

<< Where do we go from here?

Is there a way to break this cycle? >>

<<  For no matter how viscerally satisfying and rational it may appear to operate in a never-ending tit-for-tat spiral, in the long run, cooperation pays >>  

Niels Rosenquist.  How Tit-for-Tat Game Theory Hacked Politics. Jun 10, 2019. 

https://thebulwark.com/how-tit-for-tat-game-theory-has-hacked-politics/

FonT

a "catapulting" approach to bypass "lizard" brains: 

1668 - ramificata tinnula (di carmina fluitantia). Jun 9, 2005.

https://inkpi.blogspot.com/2005/06/1668-ramificata-tinnula-di-carmina.html

More

keyword "tit-for-tat" in FonT:

https://flashontrack.blogspot.com/search?q=tit-for-tat

keyword "tit-for-tat" in Notes:

https://inkpi.blogspot.com/search?q=tit-for-tat